Clinical impact of mitral calcium volume in patients undergoing transcatheter aortic valve implantation.
Aortic stenosis
Mitral annular calcification
Mitral regurgitation
Mitral stenosis
Mitral valve
Transcatheter aortic valve implantation
Journal
Journal of cardiovascular computed tomography
ISSN: 1876-861X
Titre abrégé: J Cardiovasc Comput Tomogr
Pays: United States
ID NLM: 101308347
Informations de publication
Date de publication:
Historique:
received:
22
04
2020
revised:
02
10
2020
accepted:
12
10
2020
pubmed:
31
10
2020
medline:
15
12
2021
entrez:
30
10
2020
Statut:
ppublish
Résumé
Mitral annular calcification (MAC) has been associated with mitral valve (MV) disease and cardiovascular events in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to investigate the incidence and impact of mitral calcium volume (MCV) quantified by multidetector computed tomography (MDCT) on MV function and clinical outcomes after TAVI. Consecutive patients with exploitable echocardiography and MDCT performed during TAVI screening were enrolled in this retrospective analysis. Mitral calcium was assessed visually and measured using a semi-automatic tool developed for the aortic valve in an off-label fashion. MCV >0 mm Calcification of the mitral apparatus is common in TAVI candidates and results in mitral stenosis in 25% of the patients. Increasing MCV predicts mitral stenosis, but had no impact on clinical outcomes following TAVI. NCT01368250.
Sections du résumé
BACKGROUND
BACKGROUND
Mitral annular calcification (MAC) has been associated with mitral valve (MV) disease and cardiovascular events in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to investigate the incidence and impact of mitral calcium volume (MCV) quantified by multidetector computed tomography (MDCT) on MV function and clinical outcomes after TAVI.
METHODS
METHODS
Consecutive patients with exploitable echocardiography and MDCT performed during TAVI screening were enrolled in this retrospective analysis. Mitral calcium was assessed visually and measured using a semi-automatic tool developed for the aortic valve in an off-label fashion.
RESULTS
RESULTS
MCV >0 mm
CONCLUSIONS
CONCLUSIONS
Calcification of the mitral apparatus is common in TAVI candidates and results in mitral stenosis in 25% of the patients. Increasing MCV predicts mitral stenosis, but had no impact on clinical outcomes following TAVI.
CLINICAL TRIAL REGISTRATION
BACKGROUND
NCT01368250.
Identifiants
pubmed: 33121904
pii: S1934-5925(20)30465-2
doi: 10.1016/j.jcct.2020.10.003
pii:
doi:
Substances chimiques
Calcium
SY7Q814VUP
Banques de données
ClinicalTrials.gov
['NCT01368250']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
356-365Informations de copyright
Copyright © 2020 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.