Adult-Onset ANCA-Associated Vasculitis in SAVI: Extension of the Phenotypic Spectrum, Case Report and Review of the Literature.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2020
Historique:
received: 22 06 2020
accepted: 10 09 2020
entrez: 2 11 2020
pubmed: 3 11 2020
medline: 16 6 2021
Statut: epublish

Résumé

STING-associated vasculopathy with onset in infancy (SAVI) is an autosomal dominant disorder due to gain-of-function mutations in

Identifiants

pubmed: 33133092
doi: 10.3389/fimmu.2020.575219
pmc: PMC7550674
doi:

Substances chimiques

Membrane Proteins 0
STING1 protein, human 0

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

575219

Informations de copyright

Copyright © 2020 Staels, Betrains, Doubel, Willemsen, Cleemput, Vanderschueren, Corveleyn, Meyts, Sprangers, Crow, Humblet-Baron, Liston and Schrijvers.

Références

J Clin Invest. 2014 Dec;124(12):5516-20
pubmed: 25401470
N Engl J Med. 2014 Aug 7;371(6):507-518
pubmed: 25029335
JAMA Dermatol. 2015 Aug;151(8):872-7
pubmed: 25992765
Chest. 2016 Sep;150(3):e65-71
pubmed: 27613991
Am J Kidney Dis. 2020 Feb;75(2):287-290
pubmed: 31601430
J Exp Med. 2017 Jun 5;214(6):1769-1785
pubmed: 28484079

Auteurs

Frederik Staels (F)

Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, KU Leuven, Leuven, Belgium.
Department of Microbiology, Immunology and Transplantation, Immunogenetics Research Group, KU Leuven, Leuven, Belgium.

Albrecht Betrains (A)

Department of Microbiology, Immunology and Transplantation, Laboratory for Clinical Infectious and Inflammatory Disease, KU Leuven, Leuven, Belgium.

Peter Doubel (P)

Department of Nephrology, AZ Groeninge, Kortrijk, Belgium.

Mathijs Willemsen (M)

Department of Microbiology, Immunology and Transplantation, Immunogenetics Research Group, KU Leuven, Leuven, Belgium.
VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.

Vincent Cleemput (V)

Department of Pathology, University Hospitals KU Leuven, Leuven, Belgium.

Steven Vanderschueren (S)

Department of Microbiology, Immunology and Transplantation, Laboratory for Clinical Infectious and Inflammatory Disease, KU Leuven, Leuven, Belgium.

Anniek Corveleyn (A)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, Leuven, Belgium.

Isabelle Meyts (I)

Laboratory of Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.

Ben Sprangers (B)

Department of Microbiology, Immunology and Transplantation, Molecular Immunology, KU Leuven, Leuven, Belgium.

Yanick J Crow (YJ)

Centre for Genomic Medicine, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, United Kingdom.
Laboratory of Neurogenetics and Neuroinflammation, Université de Paris, Paris, France.

Stephanie Humblet-Baron (S)

Department of Microbiology, Immunology and Transplantation, Immunogenetics Research Group, KU Leuven, Leuven, Belgium.

Adrian Liston (A)

Department of Microbiology, Immunology and Transplantation, Immunogenetics Research Group, KU Leuven, Leuven, Belgium.
Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.

Rik Schrijvers (R)

Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, KU Leuven, Leuven, Belgium.
Department of Microbiology, Immunology and Transplantation, Immunogenetics Research Group, KU Leuven, Leuven, Belgium.

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Classifications MeSH