Comorbidities, anthropometric, demographic, and lifestyle risk factors for ulnar neuropathy at the elbow: A case control study.


Journal

Journal of the peripheral nervous system : JPNS
ISSN: 1529-8027
Titre abrégé: J Peripher Nerv Syst
Pays: United States
ID NLM: 9704532

Informations de publication

Date de publication:
12 2020
Historique:
received: 25 09 2020
revised: 22 10 2020
accepted: 26 10 2020
pubmed: 4 11 2020
medline: 28 9 2021
entrez: 3 11 2020
Statut: ppublish

Résumé

We performed a prospective multicenter case-control study to explore the association between ulnar neuropathy at elbow (UNE) and body and elbow anthropometric measures, demographic and lifestyle factors, and comorbidities. Cases and controls were consecutively enrolled among subjects admitted to four electromyography labs. UNE diagnosis was made on clinical and neurographic findings. The control group included all other subjects without signs/symptoms of ulnar neuropathy and with normal ulnar nerve neurography. Anthropometric measurements included weight, height, waist, hip circumferences, and external measures of elbow using a caliper. The participants filled in a self-administered questionnaire on personal characteristics, lifestyle factors, and medical history. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) by fitting unconditional logistic regression models adjusted by center and education level. We enrolled 220 cases (males 61.8%; mean age 51.7 years) and 460 controls (47.4% males; mean age 47.8 years). At multivariable analysis, UNE was associated to male gender (OR = 2.4, 95%CI = 1.6-3.7), smoking habits (>25 pack-years (OR = 2.3, 95%CI = 1.3-4.1), body mass index (OR = 1.05, 95%CI 1.01-1.10), polyneuropathies (OR = 4.1, 95%CI 1.5-11.5), and leaning with flexed elbow on a table/desk (OR = 1.5, 95%CI 1.0-2.2). Cubital groove width (CGW) turned out to be negatively associated with UNE (OR = 0.80, 95%CI = 0.74-0.85). Our study suggests that some personal factors especially anthropometric measures of the elbow may play a role in UNE pathogenesis as the measures of wrist in CTS. We demonstrated that for each millimeter of smaller CGW the risk of idiopathic UNE increases of 25%.

Identifiants

pubmed: 33140525
doi: 10.1111/jns.12420
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

401-412

Informations de copyright

© 2020 Peripheral Nerve Society.

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Auteurs

Mauro Mondelli (M)

EMG Service, Local Health Unit Toscana Sud Est, Siena, Italy.

Stefano Mattioli (S)

Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Claudia Vinciguerra (C)

EMG Service, Local Health Unit Toscana Sud Est, Siena, Italy.
Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.

Palma Ciaramitaro (P)

Clinical Neurophysiology, CTO, Department of Neuroscience, AOU "Città della Salute e della Scienza", Torino, Italy.

Alessandro Aretini (A)

EMG Service, Local Health Unit Toscana Sud Est, Siena, Italy.

Giuseppe Greco (G)

EMG Service, Local Health Unit Toscana Sud Est, "Nottola" Hospital, Montepulciano, Siena, Italy.

Francesco Sicurelli (F)

Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.

Stefano Giorgi (S)

Clinical Neurophysiology, CTO, Department of Neuroscience, AOU "Città della Salute e della Scienza", Torino, Italy.

Stefania Curti (S)

Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

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