COVID-19 hospital outbreaks: Protecting healthcare workers to protect frail patients. An Italian observational cohort study.
Adult
Aged
COVID-19
/ epidemiology
Cohort Studies
Cross Infection
/ epidemiology
Disease Outbreaks
Female
Frail Elderly
/ statistics & numerical data
Health Personnel
/ statistics & numerical data
Hospitals, University
/ statistics & numerical data
Humans
Italy
/ epidemiology
Male
Middle Aged
Prevalence
Risk Factors
SARS-CoV-2
/ physiology
COVID-19
Healthcare workers
Prevention protocol
Journal
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
ISSN: 1878-3511
Titre abrégé: Int J Infect Dis
Pays: Canada
ID NLM: 9610933
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
23
09
2020
revised:
28
10
2020
accepted:
28
10
2020
pubmed:
7
11
2020
medline:
20
1
2021
entrez:
6
11
2020
Statut:
ppublish
Résumé
To determine the prevalence of SARS-CoV-2 infection among exposed healthcare workers (HCWs) after preventive protocol implementation. A total of 5750 HCWs were included in the study. Those in contact with COVID-19 patients were allocated into a high-risk or a low-risk group based on contact type (PPE- or non-PPE-protected); high-risk workers underwent nasopharyngeal swab tests, while among low-risk workers, swab tests were carried out only for symptomatic workers (active surveillance). The prevalence was determined by real-time reverse transcriptase-polymerase chain reaction on nasopharyngeal samples. 3570 HCWs had contact with 1065 COVID-19 patients. Among them, 3494 were subjected to active surveillance (low-risk group); 2886 (82.60%) were subjected to a swab test; and 15 were positive (0.52%). Seventy-six HCWs (2.13% of exposed) were included in the high-risk group, and a swab test was mandatory for each participant. Overall, 66 (86.84% of high-risk) were negative, and 10 were positive (13.16%), resulting in a higher risk of infection than in the low-risk group [OR = 29.00; 95% CI:12.56-66.94; p < 0.0001]. To date, the SARS-CoV-2 infection prevalence is 0.70% among exposed HCWs and 0.435% among all HCWs working at the examined university hospital. The correct use of PPE and the early identification of symptomatic workers are essential factors to avoiding nosocomial clusters.
Identifiants
pubmed: 33157297
pii: S1201-9712(20)32298-0
doi: 10.1016/j.ijid.2020.10.098
pmc: PMC7610093
pii:
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
532-537Informations de copyright
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
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