Comparing LAMA with LABA and LTRA as add-on therapies in primary care asthma management.


Journal

NPJ primary care respiratory medicine
ISSN: 2055-1010
Titre abrégé: NPJ Prim Care Respir Med
Pays: England
ID NLM: 101631999

Informations de publication

Date de publication:
11 11 2020
Historique:
received: 01 04 2020
accepted: 03 09 2020
entrez: 12 11 2020
pubmed: 13 11 2020
medline: 23 9 2021
Statut: epublish

Résumé

The Global Initiative for Asthma recommends a stepwise approach to adjust asthma treatment to the needs of individual patients; inhaled corticosteroids (ICS) remain the core pharmacological treatment. However, many patients remain poorly controlled, and evidence-based algorithms to decide on the best order and rationale for add-on therapies are lacking. We explore the challenges of asthma management in primary care and review outcomes from randomised controlled trials and meta-analyses comparing the long-acting muscarinic antagonist (LAMA) tiotropium with long-acting β

Identifiants

pubmed: 33177503
doi: 10.1038/s41533-020-00205-9
pii: 10.1038/s41533-020-00205-9
pmc: PMC7658210
doi:

Substances chimiques

Adrenergic beta-2 Receptor Agonists 0
Anti-Asthmatic Agents 0
Delayed-Action Preparations 0
Leukotriene Antagonists 0
Muscarinic Antagonists 0
Tiotropium Bromide XX112XZP0J

Types de publication

Comparative Study Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

50

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Auteurs

Alan Kaplan (A)

Family Physician Airways Group of Canada, University of Toronto, Toronto, ON, Canada. for4kids@gmail.com.

J Mark FitzGerald (JM)

Centre for Lung Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.

Roland Buhl (R)

Pulmonary Department, Johannes Gutenberg University Mainz, Mainz, Germany.

Christian Vogelberg (C)

Department of Pediatric Pulmonology and Allergy, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.

Eckard Hamelmann (E)

Klinik für Kinder und Jugendmedizin, Evangelisches Klinikum Bethel, Bielefeld, Germany.
Allergy Center of the Ruhr University, Bochum, Germany.

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Classifications MeSH