Consensus on the treatment of alopecia areata - Brazilian Society of Dermatology.
Adrenal cortex hormones
Alopecia areata
Consensus
Methotrexate
Therapeutics
Journal
Anais brasileiros de dermatologia
ISSN: 1806-4841
Titre abrégé: An Bras Dermatol
Pays: Spain
ID NLM: 0067662
Informations de publication
Date de publication:
Historique:
received:
02
03
2020
accepted:
15
05
2020
pubmed:
14
11
2020
medline:
30
12
2020
entrez:
13
11
2020
Statut:
ppublish
Résumé
Alopecia areata is a highly frequent disease with an impact on quality of life and several treatment options with little clinical confirmatory evidence. To disseminate the recommendations of Brazilian dermatologists with expertise in the treatment of alopecia areata. Eight specialists with expertise in alopecia areata from different university centers were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Based on the adapted DELPHI methodology, the relevant elements were considered; then, an analysis of recent literature was carried out and the consensus was written down. Consensus on the management of alopecia areata was defined with the approval of at least 70% of the panel. Intralesional injectable corticotherapy was considered the first option for localized disease in adults. In extensive cases with signs of activity, systemic corticosteroid therapy should be considered and can be used together with immunosuppressants (corticosteroid-sparing agents). The use of an immunosensitizer (diphencyprone) is an option for stable long-term cases. Evaluation of side effects is as important as the rate of hair regrowth.
Sections du résumé
BACKGROUND
BACKGROUND
Alopecia areata is a highly frequent disease with an impact on quality of life and several treatment options with little clinical confirmatory evidence.
OBJECTIVE
OBJECTIVE
To disseminate the recommendations of Brazilian dermatologists with expertise in the treatment of alopecia areata.
METHODS
METHODS
Eight specialists with expertise in alopecia areata from different university centers were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Based on the adapted DELPHI methodology, the relevant elements were considered; then, an analysis of recent literature was carried out and the consensus was written down. Consensus on the management of alopecia areata was defined with the approval of at least 70% of the panel.
RESULTS/CONCLUSIONS
CONCLUSIONS
Intralesional injectable corticotherapy was considered the first option for localized disease in adults. In extensive cases with signs of activity, systemic corticosteroid therapy should be considered and can be used together with immunosuppressants (corticosteroid-sparing agents). The use of an immunosensitizer (diphencyprone) is an option for stable long-term cases. Evaluation of side effects is as important as the rate of hair regrowth.
Identifiants
pubmed: 33183894
pii: S0365-0596(20)30235-X
doi: 10.1016/j.abd.2020.05.006
pmc: PMC7772599
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
39-52Informations de copyright
Copyright © 2020 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.
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