questionsmedicales.fr
Maladies de la peau et du tissu conjonctif
Maladies de la peau
Maladies du système pileux
Hypotrichose
Hypotrichose : Questions médicales fréquentes
Diagnostic
5
Hypotrichose
Examen physique
Tests génétiques
Biopsie cutanée
Hypotrichose
Signes cliniques
Alopécie
Troubles capillaires
Symptômes
5
Cuir chevelu
Hypotrichose
Anomalies cutanées
Hypotrichose
Démangeaisons
Hypotrichose
Prévention
5
Soins capillaires
Hypotrichose
Alimentation
Hypotrichose
Produits chimiques
Hypotrichose
Traitements
5
Greffe de cheveux
Hypotrichose
Remèdes naturels
Hypotrichose
Dermatologue
Hypotrichose
Complications
5
Complications
Hypotrichose
Complications
Hypotrichose
Qualité de vie
Hypotrichose
Facteurs de risque
5
Facteurs de risque
Hypotrichose
Maladies auto-immunes
Hypotrichose
Déséquilibres hormonaux
Hypotrichose
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Hypotrichose : Questions médicales les plus fréquentes",
"headline": "Hypotrichose : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Hypotrichose : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-06-29",
"dateModified": "2026-03-21",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Hypotrichose"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Maladies du système pileux",
"url": "https://questionsmedicales.fr/mesh/D006201",
"about": {
"@type": "MedicalCondition",
"name": "Maladies du système pileux",
"code": {
"@type": "MedicalCode",
"code": "D006201",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C17.800.329"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Pelade",
"alternateName": "Alopecia Areata",
"url": "https://questionsmedicales.fr/mesh/D000506",
"about": {
"@type": "MedicalCondition",
"name": "Pelade",
"code": {
"@type": "MedicalCode",
"code": "D000506",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C17.800.329.937.122.147"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Hypotrichose",
"alternateName": "Hypotrichosis",
"code": {
"@type": "MedicalCode",
"code": "D007039",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Poonkiat Suchonwanit",
"url": "https://questionsmedicales.fr/author/Poonkiat%20Suchonwanit",
"affiliation": {
"@type": "Organization",
"name": "*All authors are affiliated with the Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand."
}
},
{
"@type": "Person",
"name": "Regina C Betz",
"url": "https://questionsmedicales.fr/author/Regina%20C%20Betz",
"affiliation": {
"@type": "Organization",
"name": "Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany."
}
},
{
"@type": "Person",
"name": "Ming Li",
"url": "https://questionsmedicales.fr/author/Ming%20Li",
"affiliation": {
"@type": "Organization",
"name": "Department of Dermatology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China."
}
},
{
"@type": "Person",
"name": "Michel van Geel",
"url": "https://questionsmedicales.fr/author/Michel%20van%20Geel",
"affiliation": {
"@type": "Organization",
"name": "Department of Dermatology, Maastricht University Medical Center+, Maastricht, The Netherlands."
}
},
{
"@type": "Person",
"name": "Nongsak Chanasumon",
"url": "https://questionsmedicales.fr/author/Nongsak%20Chanasumon",
"affiliation": {
"@type": "Organization",
"name": ""
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Hypotrichosis with Juvenile Macular Dystrophy in a Patient with Cadherin 3 (CDH3) Mutation.",
"datePublished": "2022-Jan-00",
"url": "https://questionsmedicales.fr/article/35996915",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3126/nepjoph.v14i1.37258"
}
},
{
"@type": "ScholarlyArticle",
"name": "Efficacy and Safety of Bimatoprost 0.01% for the Treatment of Eyebrow Hypotrichosis: A Randomized, Double-Blind, Vehicle-Controlled Study.",
"datePublished": "2019-12-00",
"url": "https://questionsmedicales.fr/article/30913051",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1097/DSS.0000000000001944"
}
},
{
"@type": "ScholarlyArticle",
"name": "Cell-trafficking impairment in disease-associated LPA6 missense mutants and a potential pharmacoperone therapy for autosomal recessive woolly hair/hypotrichosis.",
"datePublished": "2023-02-19",
"url": "https://questionsmedicales.fr/article/36173926",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1093/hmg/ddac244"
}
},
{
"@type": "ScholarlyArticle",
"name": "[Genetic analysis of a child with Hypotrichosis simplex].",
"datePublished": "2024-Mar-10",
"url": "https://questionsmedicales.fr/article/38448028",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3760/cma.j.cn511374-20230131-00043"
}
},
{
"@type": "ScholarlyArticle",
"name": "A case of LSS-associated congenital nuclear cataract with hypotrichosis and literature review.",
"datePublished": "2023-07-17",
"url": "https://questionsmedicales.fr/article/37455568",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/ajmg.a.63355"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies de la peau et du tissu conjonctif",
"item": "https://questionsmedicales.fr/mesh/D017437"
},
{
"@type": "ListItem",
"position": 3,
"name": "Maladies de la peau",
"item": "https://questionsmedicales.fr/mesh/D012871"
},
{
"@type": "ListItem",
"position": 4,
"name": "Maladies du système pileux",
"item": "https://questionsmedicales.fr/mesh/D006201"
},
{
"@type": "ListItem",
"position": 5,
"name": "Hypotrichose",
"item": "https://questionsmedicales.fr/mesh/D007039"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Hypotrichose - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Hypotrichose",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2026-04-30",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Hypotrichose",
"description": "Comment diagnostique-t-on l'hypotrichose ?\nQuels tests peuvent être nécessaires ?\nL'hypotrichose est-elle héréditaire ?\nQuels signes cliniques indiquent l'hypotrichose ?\nPeut-on confondre l'hypotrichose avec d'autres conditions ?",
"url": "https://questionsmedicales.fr/mesh/D007039#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Hypotrichose",
"description": "Quels sont les symptômes de l'hypotrichose ?\nL'hypotrichose affecte-t-elle le cuir chevelu ?\nY a-t-il des symptômes associés ?\nL'hypotrichose cause-t-elle des démangeaisons ?\nLes symptômes varient-ils d'une personne à l'autre ?",
"url": "https://questionsmedicales.fr/mesh/D007039#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Hypotrichose",
"description": "Peut-on prévenir l'hypotrichose ?\nLes soins capillaires aident-ils ?\nL'alimentation joue-t-elle un rôle ?\nLe stress influence-t-il l'hypotrichose ?\nLes produits chimiques affectent-ils les cheveux ?",
"url": "https://questionsmedicales.fr/mesh/D007039#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Hypotrichose",
"description": "Quels traitements existent pour l'hypotrichose ?\nLes greffes de cheveux sont-elles une option ?\nLes traitements sont-ils efficaces ?\nY a-t-il des remèdes naturels ?\nFaut-il consulter un dermatologue ?",
"url": "https://questionsmedicales.fr/mesh/D007039#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Hypotrichose",
"description": "Quelles complications peuvent survenir ?\nL'hypotrichose peut-elle entraîner des infections ?\nY a-t-il des risques psychologiques ?\nLes complications sont-elles fréquentes ?\nL'hypotrichose affecte-t-elle la qualité de vie ?",
"url": "https://questionsmedicales.fr/mesh/D007039#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Hypotrichose",
"description": "Quels sont les facteurs de risque de l'hypotrichose ?\nLes maladies auto-immunes sont-elles un facteur ?\nL'âge influence-t-il l'hypotrichose ?\nLes déséquilibres hormonaux sont-ils un risque ?\nLe mode de vie influence-t-il l'hypotrichose ?",
"url": "https://questionsmedicales.fr/mesh/D007039#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostique-t-on l'hypotrichose ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur l'examen physique et l'historique médical du patient."
}
},
{
"@type": "Question",
"name": "Quels tests peuvent être nécessaires ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques ou des biopsies cutanées peuvent être réalisés pour confirmer le diagnostic."
}
},
{
"@type": "Question",
"name": "L'hypotrichose est-elle héréditaire ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines formes d'hypotrichose sont héréditaires et peuvent être liées à des mutations génétiques."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent l'hypotrichose ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une diminution des cheveux sur le cuir chevelu et d'autres zones du corps est un signe clé."
}
},
{
"@type": "Question",
"name": "Peut-on confondre l'hypotrichose avec d'autres conditions ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut être confondue avec l'alopécie ou d'autres troubles capillaires."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes de l'hypotrichose ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les principaux symptômes incluent une perte de cheveux et une diminution des poils corporels."
}
},
{
"@type": "Question",
"name": "L'hypotrichose affecte-t-elle le cuir chevelu ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut affecter le cuir chevelu, entraînant une chevelure clairsemée."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes associés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies cutanées ou des problèmes de peau peuvent également être présents."
}
},
{
"@type": "Question",
"name": "L'hypotrichose cause-t-elle des démangeaisons ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, l'hypotrichose ne provoque généralement pas de démangeaisons."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et l'étendue des symptômes peuvent varier selon les individus."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'hypotrichose ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de méthode garantie pour prévenir l'hypotrichose, surtout si elle est héréditaire."
}
},
{
"@type": "Question",
"name": "Les soins capillaires aident-ils ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des soins capillaires appropriés peuvent aider à maintenir la santé des cheveux, mais ne préviennent pas l'hypotrichose."
}
},
{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut favoriser la santé des cheveux, mais ne prévient pas l'hypotrichose."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il l'hypotrichose ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut aggraver certains types de perte de cheveux, mais n'est pas une cause directe de l'hypotrichose."
}
},
{
"@type": "Question",
"name": "Les produits chimiques affectent-ils les cheveux ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'utilisation excessive de produits chimiques peut endommager les cheveux, mais ne cause pas l'hypotrichose."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour l'hypotrichose ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des thérapies topiques et des médicaments pour stimuler la croissance des cheveux."
}
},
{
"@type": "Question",
"name": "Les greffes de cheveux sont-elles une option ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les greffes de cheveux peuvent être envisagées dans certains cas d'hypotrichose."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité des traitements varie selon la cause sous-jacente de l'hypotrichose."
}
},
{
"@type": "Question",
"name": "Y a-t-il des remèdes naturels ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains remèdes naturels, comme les huiles essentielles, sont parfois utilisés, mais leur efficacité n'est pas prouvée."
}
},
{
"@type": "Question",
"name": "Faut-il consulter un dermatologue ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un dermatologue peut fournir des conseils et des traitements adaptés à l'hypotrichose."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des problèmes d'estime de soi et des troubles psychologiques liés à l'apparence."
}
},
{
"@type": "Question",
"name": "L'hypotrichose peut-elle entraîner des infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, l'hypotrichose en elle-même ne cause pas d'infections, mais une peau exposée peut être vulnérable."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques psychologiques ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'hypotrichose peut entraîner des problèmes d'anxiété ou de dépression chez certains patients."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles fréquentes ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications psychologiques sont fréquentes, mais varient d'une personne à l'autre."
}
},
{
"@type": "Question",
"name": "L'hypotrichose affecte-t-elle la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut affecter la qualité de vie en raison de l'impact sur l'image corporelle."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'hypotrichose ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des maladies génétiques et des troubles hormonaux."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un facteur ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies auto-immunes peuvent contribuer à l'hypotrichose."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il l'hypotrichose ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'hypotrichose peut survenir à tout âge, mais certaines formes sont plus fréquentes chez les enfants."
}
},
{
"@type": "Question",
"name": "Les déséquilibres hormonaux sont-ils un risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les déséquilibres hormonaux peuvent affecter la croissance des cheveux et contribuer à l'hypotrichose."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il l'hypotrichose ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire certains risques, mais ne prévient pas l'hypotrichose."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 21/03/2026
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
*All authors are affiliated with the Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Publications dans "Hypotrichose" :
2 publications dans cette catégorie
Affiliations :
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Publications dans "Hypotrichose" :
2 publications dans cette catégorie
Affiliations :
Department of Dermatology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Publications dans "Hypotrichose" :
2 publications dans cette catégorie
Affiliations :
Department of Dermatology, Maastricht University Medical Center+, Maastricht, The Netherlands.
GROW Research School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, The Netherlands.
Publications dans "Hypotrichose" :
2 publications dans cette catégorie
Publications dans "Hypotrichose" :
2 publications dans cette catégorie
Affiliations :
All authors are affiliated with the Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Department of Dermatology, Jining No.1 People's Hospital, Jining, Shandong 272002, China. wangjianbo1020@163.com.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Clinic for Reproduction and Large Animals, University of Ljubljana Veterinary Faculty, Cesta v Mestni log 47, 1000, Ljubljana, Slovenia.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Institute of Pathology, Wild Animals, Fish and Bees, University of Ljubljana Veterinary Faculty, Gerbičeva 60, 1000, Ljubljana, Slovenia.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Clinic for Reproduction and Large Animals, University of Ljubljana Veterinary Faculty, Cesta v Mestni log 47, 1000, Ljubljana, Slovenia.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Institute of Pathology, Wild Animals, Fish and Bees, University of Ljubljana Veterinary Faculty, Gerbičeva 60, 1000, Ljubljana, Slovenia.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Publications dans "Hypotrichose" :
1 publication dans cette catégorie
Affiliations :
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Publications dans "Hypotrichose" :
Hypotrichosis with juvenile macular dystrophy (HJMD) is an autosomal recessive disease with progressive macular degeneration leading to blindness in the first three decades of life along with hypotric...
We herein report a case of a five year old boy with hypotrichosis with juvenile macular dystrophy diagnosed with multi-modal imaging which was later confirmed by genetic testing by whole genome sequen...
Fundus examination of both eyes revealed symmetrical hypopigmentation in peripapillary retinal pigment epithelium (RPE) involving posterior pole and surrounded by a mottled hyperpigmented border. Fund...
Children with reduced vision not falling into a typical macular degeneration should be examined systemically and may just have sparse scalp hair and still have a genetic disease. A regular follow-up s...
Eyebrow hypotrichosis is an important dermatological problem. However, there is no standard treatment....
To study the efficacy and safety of bimatoprost 0.01% for the treatment of eyebrow hypotrichosis....
Although bimatoprost 0.03% has been studied previously, this is the first study to evaluate the efficacy and safety of bimatoprost 0.01% for the treatment of eyebrow hypotrichosis. A randomized, doubl...
Compared to the vehicle group, bimatoprost 0.01% significantly increased mean eyebrow hair density, eyebrow hair diameter, and clinical assessments (p < .001) in the drug group. Patients' satisfaction...
Bimatoprost 0.01% was found to be superior to a placebo for eyebrow enhancement. Bimatoprost 0.01% can be considered effective, safe, and well-tolerated for the treatment of eyebrow hypotrichosis....
In human autosomal recessive woolly hair/hypotrichosis (ARWH/HT), many mutations have been identified in a gene encoding LPA6, a G protein-coupled receptor (GPCR) for lysophosphatidic acid (LPA). Howe...
To explore the clinical phenotype and genetic characteristics of a child with Hypotrichosis 14....
A child who had presented at the Henan Provincial People's Hospital on May 4, 2020 due to hair thinning was selected as the study subject. Clinical data of the child was collected. Peripheral venous b...
The child, a 5-year-old female, had presented with thin, soft lanugo-like hair which was easy to fall off. The child was found to harbor compound heterozygous missense variants of the LSS gene, namely...
The c.1609G>A (p.V537M) and c.802T>G (p.F268V) compound heterozygous variants of the LSS gene probably underlay the clinical phenotype in this patient....
Congenital cataract is the most common cause of lifelong visual loss in children worldwide, which has significant genotypic and phenotypic heterogeneity. The LSS gene encodes lanosterol synthase (LSS)...
To explore the genetic etiology of a girl featuring epilepsy, speech delay and mild mental retardation....
Peripheral blood samples of the child and her parents were collected. Genomic DNA was extracted and subjected to next generation sequencing. Suspected variant was confirmed by Sanger sequencing....
The child was found to carry a de novo heterozygous c.3592G>A (p.V1198M) variant of the SMARCA2 gene, which was predicted to be pathogenic by bioinformatic analysis....
The child was diagnosed with Nicolaides-Baraitser syndrome due to heterozygous variant of the SMARCA2 gene....
Genetic diseases with hyper- and hypotrichosis are very heterogeneous, both clinically and genetically. This is especially true for ectodermal dysplasias but also for hereditary syndromes in which, be...
The FDA approved bimatoprost ophthalmic solution 0.03% for treatment of eyelash hypotrichosis in 2008. Consumer concern persists regarding potential side effects of this product....
To identify gaps in the safety information associated with the use of prostaglandin eyelash growth products....
Literature searches were performed using PubMed, Embase, and Nexis Uni databases without restriction to publication date, language, or study setting....
The literature pertaining to bimatoprost for treatment of eyelash hypotrichosis is dominated by industry-sponsored clinical trials. Study design choices create gaps in our understanding of the clinica...
Because of study design choice, clinical trials of bimatoprost for eyelash growth may have systematically underreported the incidence of drug application discomfort and prostaglandin-associated perior...
Coffin-Siris syndrome (CSS) and Nicolaides-Baraitser syndrome (NBS) are 2 overlapping syndromes caused by mutations in genes of the barrier-to-autointegration factor chromatin-remodeling complex, pres...
Skin diseases represent the second most common paraneoplastic manifestations after endocrine disorders. Paraneoplastic dermatoses may arise as the first clinical sign of occult malignancies, or manife...