Gallium-Based Liquid Metal Particles for Therapeutics.

Alloys / chemistry Drug Delivery Systems Gallium / chemistry
gallium liquid metal particles therapeutics

Journal

Trends in biotechnology
ISSN: 1879-3096
Titre abrégé: Trends Biotechnol
Pays: England
ID NLM: 8310903

Informations de publication

Date de publication:
06 2021
Historique:
received: 08 09 2020
revised: 09 10 2020
accepted: 12 10 2020
pubmed: 18 11 2020
medline: 7 10 2021
entrez: 17 11 2020
Statut: ppublish

Résumé

Gallium (Ga) and Ga-based liquid metal (LM) alloys offer low toxicity, excellent electrical and thermal conductivities, and fluidity at or near room temperature. Ga-based LM particles (LMPs) synthesized from these LMs exhibit both fluidic and metallic properties and are suitable for versatile functionalization in therapeutics. Functionalized Ga-based LMPs can be actuated using physical or chemical stimuli for drug delivery, cancer treatment, bioimaging, and biosensing. However, many of the fundamentals of their unique characteristics for therapeutics remain underexplored. We present the most recent advances in Ga-based LMPs in therapeutics based on the underlying mechanisms of their design and implementation. We also highlight some future biotechnological opportunities for Ga-based LMPs based on their extraordinary advantages.

Identifiants

DOI: 10.1016/j.tibtech.2020.10.005 PMID: 33199046
pubmed: 33199046
pii: S0167-7799(20)30269-9
doi: 10.1016/j.tibtech.2020.10.005
pii:
doi:

Substances chimiques

Alloys 0
Gallium CH46OC8YV4

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

624-640

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Wanjie Xie (W)

School of Chemical Engineering, University of New South Wales, Kensington, NSW 2052, Australia.

Francois-Marie Allioux (FM)

School of Chemical Engineering, University of New South Wales, Kensington, NSW 2052, Australia.

Jian Zhen Ou (JZ)

School of Engineering, RMIT University, Melbourne, VIC 3001, Australia.

Eijiro Miyako (E)

Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan.

Shi-Yang Tang (SY)

Department of Electronic, Electrical and Systems Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Kourosh Kalantar-Zadeh (K)

School of Chemical Engineering, University of New South Wales, Kensington, NSW 2052, Australia. Electronic address: k.kalantar-zadeh@unsw.edu.au.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Alliages › Gallium-Based Liquid Metal Particles for Therapeutics.
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Gallium-Based Liquid Metal Particles for Therapeutics.
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Gallium › Gallium-Based Liquid Metal Particles for Therapeutics.