Pharmacological Actions of Carbamate Insecticides at Mammalian Melatonin Receptors.

Animals Binding Sites Brain / drug effects CHO Cells Carbamates / pharmacokinetics Circadian Rhythm / drug effects Cricetinae Cricetulus Humans Insecticides / pharmacokinetics Male Mice Molecular Docking Simulation Protein Binding Receptors, Melatonin / chemistry

Journal

The Journal of pharmacology and experimental therapeutics
ISSN: 1521-0103
Titre abrégé: J Pharmacol Exp Ther
Pays: United States
ID NLM: 0376362

Informations de publication

Date de publication:
02 2021
Historique:
received: 22 04 2020
accepted: 11 11 2020
pubmed: 19 11 2020
medline: 1 5 2021
entrez: 18 11 2020
Statut: ppublish

Résumé

Integrated in silico chemical clustering and melatonin receptor molecular modeling combined with in vitro 2-[

Identifiants

DOI: 10.1124/jpet.120.000065 PMID: 33203660 PMC: PMC7841424
pubmed: 33203660
pii: jpet.120.000065
doi: 10.1124/jpet.120.000065
pmc: PMC7841424
doi:

Substances chimiques

Carbamates 0
Insecticides 0
Receptors, Melatonin 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

306-321

Subventions

Organisme : NIDA NIH HHS
ID : HHSN271201800023C
Pays : United States

Informations de copyright

Copyright © 2021 by The American Society for Pharmacology and Experimental Therapeutics.

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Auteurs

Grant C Glatfelter (GC)

Department of Pharmacology and Toxicology (G.C.G., A.J.J., R.V.R., M.L.D.), Interdepartmental Neuroscience Program (A.J.J., M.L.D.), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.

Anthony J Jones (AJ)

Department of Pharmacology and Toxicology (G.C.G., A.J.J., R.V.R., M.L.D.), Interdepartmental Neuroscience Program (A.J.J., M.L.D.), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.

Rajendram V Rajnarayanan (RV)

Department of Pharmacology and Toxicology (G.C.G., A.J.J., R.V.R., M.L.D.), Interdepartmental Neuroscience Program (A.J.J., M.L.D.), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.

Margarita L Dubocovich (ML)

Department of Pharmacology and Toxicology (G.C.G., A.J.J., R.V.R., M.L.D.), Interdepartmental Neuroscience Program (A.J.J., M.L.D.), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York mdubo@buffalo.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Carbamates › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes chronobiologiques › Périodicité › Rythme circadien › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Pesticides › Insecticides › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Pharmacological Actions of Carbamate...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Récepteurs cytoplasmiques et nucléaires › Récepteurs à la mélatonine › Pharmacological Actions of Carbamate...