Association of hyperuricemia and gamma glutamyl transferase as a marker of metabolic risk in alcohol use disorder.
Adult
Alcoholism
/ physiopathology
Biomarkers
/ analysis
Body Mass Index
Cross-Sectional Studies
Female
Glomerular Filtration Rate
Humans
Hyperuricemia
/ complications
Liver Cirrhosis
/ blood
Male
Metabolic Syndrome
/ blood
Middle Aged
Prevalence
Risk Factors
Spain
/ epidemiology
Uric Acid
/ blood
gamma-Glutamyltransferase
/ blood
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
18 11 2020
18 11 2020
Historique:
received:
06
07
2020
accepted:
04
11
2020
entrez:
19
11
2020
pubmed:
20
11
2020
medline:
31
3
2021
Statut:
epublish
Résumé
Excessive alcohol consumption leads to overproduction of urates and renal function plays a critical role in serum uric acid levels. We aimed to assess associations of hyperuricemia in patients with alcohol use disorder (AUD) and comparable Glomerular Filtration Rate (GFR). A total of 686 patients undergoing treatment for AUD between 2013 and 2017 were eligible (77% men); age at admission was 47 years [interquartile range (IQR), 40-53 years], age of onset of alcohol consumption was 16 years [IQR, 16-18 years] and the amount of alcohol consumed was 160 g/day [IQR, 120-240 g/day]. Body Mass Index was 24.7 kg/m
Identifiants
pubmed: 33208850
doi: 10.1038/s41598-020-77013-1
pii: 10.1038/s41598-020-77013-1
pmc: PMC7674473
doi:
Substances chimiques
Biomarkers
0
Uric Acid
268B43MJ25
gamma-Glutamyltransferase
EC 2.3.2.2
gamma-glutamyltransferase, human
EC 2.3.2.2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20060Commentaires et corrections
Type : ErratumIn
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