Genomic and Transcriptomic Analysis for Identification of Genes and Interlinked Pathways Mediating Artemisinin Resistance in

Animals Antiprotozoal Agents / pharmacology Aquaglyceroporins / genetics Artemisinins / pharmacology Artesunate / pharmacology Chromosomes Drug Resistance / drug effects Gene Expression / drug effects Gene Frequency Genome, Protozoan HSP70 Heat-Shock Proteins / genetics Humans Leishmania donovani / drug effects Leishmaniasis, Visceral / parasitology Mice Protozoan Proteins / genetics Reproducibility of Results Whole Genome Sequencing
Leishmania donovani artemisinin drug resistance transcriptome whole-genome sequencing (WGS)

Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
17 11 2020
Historique:
received: 24 08 2020
revised: 11 09 2020
accepted: 14 09 2020
entrez: 20 11 2020
pubmed: 21 11 2020
medline: 23 7 2021
Statut: epublish

Résumé

Current therapy for visceral leishmaniasis (VL), compromised by drug resistance, toxicity, and high cost, demands for more effective, safer, and low-cost drugs. Artemisinin has been found to be an effectual drug alternative in experimental models of leishmaniasis. Comparative genome and transcriptome analysis of in vitro-adapted artesunate-resistant (K133AS-R) and -sensitive wild-type (K133WT)

Identifiants

DOI: 10.3390/genes11111362 PMID: 33213096 PMC: PMC7698566
pubmed: 33213096
pii: genes11111362
doi: 10.3390/genes11111362
pmc: PMC7698566
pii:
doi:

Substances chimiques

Antiprotozoal Agents 0
Aquaglyceroporins 0
Artemisinins 0
HSP70 Heat-Shock Proteins 0
Protozoan Proteins 0
Artesunate 60W3249T9M

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Références

Int J Parasitol Drugs Drug Resist. 2014 Sep 22;5(1):26-35
pubmed: 25941624
J Biomed Biotechnol. 2010;2010:617521
pubmed: 19888437
Mol Microbiol. 2013 Apr;88(1):189-202
pubmed: 23421749
Int J Parasitol. 2003 Sep 30;33(11):1173-81
pubmed: 13678633
Antimicrob Agents Chemother. 2015 Jul;59(7):3870-9
pubmed: 25870074
Bioinformatics. 2009 Aug 15;25(16):2078-9
pubmed: 19505943
Eukaryot Cell. 2006 Oct;5(10):1713-25
pubmed: 17030997
Nat Ecol Evol. 2017 Dec;1(12):1961-1969
pubmed: 29109466
Int J Nanomedicine. 2017 Mar 20;12:2189-2204
pubmed: 28356736
Trop Med Int Health. 2014 Feb;19(2):146-52
pubmed: 24433217
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
Antimicrob Agents Chemother. 2005 Jul;49(7):2677-86
pubmed: 15980336
F1000Res. 2017 May 26;6:750
pubmed: 28649370
Front Microbiol. 2014 Nov 25;5:626
pubmed: 25505453
Science. 2011 Jul 22;333(6041):463-7
pubmed: 21778402
Antimicrob Agents Chemother. 2004 Jul;48(7):2409-14
pubmed: 15215088
Parasitol Res. 2012 Jul;111(1):223-30
pubmed: 22302478
J Antimicrob Chemother. 2010 Mar;65(3):496-507
pubmed: 20067981
Mol Microbiol. 2005 Sep;57(6):1690-9
pubmed: 16135234
Cell. 2008 Jan 11;132(1):27-42
pubmed: 18191218
Clin Infect Dis. 2013 Jun;56(11):1530-8
pubmed: 23425958
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W293-7
pubmed: 16845012
Parasitol Res. 2019 Sep;118(9):2705-2713
pubmed: 31359134
Biol Cell. 2005 Jun;97(6):373-83
pubmed: 15901246
Antimicrob Agents Chemother. 2014 May;58(5):2580-5
pubmed: 24550335
Mol Microbiol. 2007 Jun;64(5):1141-53
pubmed: 17542911
Bioinformatics. 2014 Aug 1;30(15):2114-20
pubmed: 24695404
Mol Biochem Parasitol. 2005 Apr;140(2):205-20
pubmed: 15760660
Antimicrob Agents Chemother. 2009 Jun;53(6):2646-9
pubmed: 19307364
Nucleic Acids Res. 2011 Sep 1;39(17):7499-511
pubmed: 21693561
J Cell Sci. 2008 Mar 1;121(Pt 5):561-70
pubmed: 18252798
PLoS One. 2016 Apr 28;11(4):e0154101
pubmed: 27123924
mBio. 2017 May 23;8(3):
pubmed: 28536289
Clin Infect Dis. 2012 Aug;55(4):543-50
pubmed: 22573856
Mol Microbiol. 2016 Feb;99(3):597-610
pubmed: 26481108
Mol Biochem Parasitol. 2008 Dec;162(2):155-64
pubmed: 18796316
Iran J Parasitol. 2015 Apr-Jun;10(2):258-67
pubmed: 26246824
Sci Rep. 2019 Apr 16;9(1):6127
pubmed: 30992521
Drug Resist Updat. 2004 Aug-Oct;7(4-5):257-66
pubmed: 15533763
Nature. 2014 Jan 2;505(7481):50-5
pubmed: 24352242
Mediators Inflamm. 2015;2015:835910
pubmed: 26538837
Genome Biol. 2008;9(7):R115
pubmed: 18638379
Antimicrob Agents Chemother. 2012 Feb;56(2):1031-41
pubmed: 22123699
Nature. 2014 Jul 17;511(7509):344-7
pubmed: 24896178
Antimicrob Agents Chemother. 2003 Aug;47(8):2397-403
pubmed: 12878496
Free Radic Res. 2010 Nov;44(11):1289-95
pubmed: 20815780
Genome Res. 2011 Dec;21(12):2143-56
pubmed: 22038251
J Med Microbiol. 2007 Sep;56(Pt 9):1213-1218
pubmed: 17761485
J Biol Chem. 2006 Aug 18;281(33):23766-75
pubmed: 16785229
Parasitol Res. 2014 Mar;113(3):1171-84
pubmed: 24449447
Nucleic Acids Res. 2009 Apr;37(5):1387-99
pubmed: 19129236
Trends Parasitol. 2017 Mar;33(3):162-174
pubmed: 27993477
BMC Genomics. 2018 Nov 28;19(1):843
pubmed: 30486770
Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):240-5
pubmed: 23248304
PLoS One. 2012;7(5):e35671
pubmed: 22693548
Genome Res. 2001 Aug;11(8):1425-33
pubmed: 11483584
Fly (Austin). 2012 Apr-Jun;6(2):80-92
pubmed: 22728672
Bioinformatics. 2005 Sep 15;21(18):3674-6
pubmed: 16081474
Biomed Res Int. 2014;2014:215872
pubmed: 24575401
Nat Commun. 2018 Sep 18;9(1):3801
pubmed: 30228310
Meta Gene. 2014 Oct 24;2:782-98
pubmed: 25606461
Mol Microbiol. 2013 Aug;89(3):565-82
pubmed: 23782314
Genome Res. 2002 Apr;12(4):656-64
pubmed: 11932250
Mol Biochem Parasitol. 2009 Apr;164(2):111-7
pubmed: 19146886
Iran J Pharm Res. 2013 Fall;12(4):903-9
pubmed: 24523770
J Immunol. 2004 Apr 15;172(8):4902-6
pubmed: 15067069
Colloids Surf B Biointerfaces. 2015 Jun 1;130:215-21
pubmed: 25936561
Nucleic Acids Res. 1997 Sep 1;25(17):3389-402
pubmed: 9254694
Parasit Vectors. 2017 Jan 31;10(1):49
pubmed: 28137296
Mol Biol Evol. 2010 Jan;27(1):33-45
pubmed: 19748930
PLoS Negl Trop Dis. 2017 Jun 2;11(6):e0005641
pubmed: 28575060
Genome Res. 2011 Jun;21(6):974-84
pubmed: 21324876
Int J Antimicrob Agents. 2007 Sep;30(3):229-35
pubmed: 17628445
Mol Biochem Parasitol. 2004 Dec;138(2):165-70
pubmed: 15555728
Front Plant Sci. 2016 Apr 12;7:481
pubmed: 27148308
Parasitol Res. 2019 May;118(5):1609-1623
pubmed: 30903348
Lancet. 2018 Sep 15;392(10151):951-970
pubmed: 30126638
Int J Parasitol Drugs Drug Resist. 2017 Dec;7(3):370-377
pubmed: 29035735
Genome Res. 2016 Feb;26(2):183-91
pubmed: 26755636
Emerg Infect Dis. 2012 Apr;18(4):704-6
pubmed: 22469394

Auteurs

Sushmita Ghosh (S)

ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
JH-Institute of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India.

Aditya Verma (A)

ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.

Vinay Kumar (V)

ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
ORCID: 0000-0002-8075-1431

Dibyabhaba Pradhan (D)

ICMR-AIIMS Computational Genomics Centre, Indian Council of Medical Research, New Delhi 110029, India.
ORCID: 0000-0002-2459-5032

Angamuthu Selvapandiyan (A)

JH-Institute of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India.

Poonam Salotra (P)

ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.

Ruchi Singh (R)

ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
ORCID: 0000-0001-8094-4703

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Porines › Aquaporines › Aquaglycéroporines › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Sesquiterpènes › Artémisinines › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Sesquiterpènes › Artémisinines › Artésunate › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Chromosomes › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Phénomènes génétiques › Fréquence d'allèle › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome de protozoaire › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Chaperons moléculaires › Protéines du choc thermique › Protéines du choc thermique HSP70 › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Eucaryotes › Euglénozoaires › Kinetoplastida › Trypanosomatina › Leishmania › Leishmania donovani › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Infection › Maladies vectorielles › Leishmaniose viscérale › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de protozoaire › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Reproductibilité des résultats › Genomic and Transcriptomic Analysis for...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ADN › Séquençage du génome entier › Genomic and Transcriptomic Analysis for...