COVID-19: A review of therapeutic strategies and vaccine candidates.
Journal
Clinical immunology (Orlando, Fla.)
ISSN: 1521-7035
Titre abrégé: Clin Immunol
Pays: United States
ID NLM: 100883537
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
13
11
2020
accepted:
13
11
2020
pubmed:
21
11
2020
medline:
29
1
2021
entrez:
20
11
2020
Statut:
ppublish
Résumé
The world is engulfed by one of the most widespread and significant public health crises in decades as COVID-19 has become among the leading causes of death internationally. The novel SARS-CoV-2 coronavirus which causes COVID-19 has unified the scientific community in search of therapeutic and preventative solutions. The top priorities at the moment are twofold: first, to repurpose already-approved pharmacologic agents or develop novel therapies to reduce the morbidity and mortality associated with the ever-spreading virus. Secondly, the scientific and larger pharmaceutical community have been tasked with the development, testing, and production of a safe and effective vaccine as a longer-term solution to prevent further spread and recurrence throughout the populace. The purpose of this article is to review the most up-to-date published data regarding both the leading pharmacological therapies undergoing clinical trials and vaccine candidates in development to stem the threat of COVID-19.
Identifiants
pubmed: 33217545
pii: S1521-6616(20)30794-4
doi: 10.1016/j.clim.2020.108634
pmc: PMC7670907
pii:
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Antiviral Agents
0
COVID-19 Vaccines
0
Complement Inactivating Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
108634Subventions
Organisme : NIAMS NIH HHS
ID : R61 AR078075
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR076440
Pays : United States
Organisme : NIAMS NIH HHS
ID : K08 AR070891
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
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