The Impact of SARS-CoV-2 on Stroke Epidemiology and Care: A Meta-Analysis.


Journal

Annals of neurology
ISSN: 1531-8249
Titre abrégé: Ann Neurol
Pays: United States
ID NLM: 7707449

Informations de publication

Date de publication:
02 2021
Historique:
received: 18 08 2020
revised: 15 11 2020
accepted: 17 11 2020
pubmed: 22 11 2020
medline: 30 1 2021
entrez: 21 11 2020
Statut: ppublish

Résumé

Emerging data indicate an increased risk of cerebrovascular events with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and highlight the potential impact of coronavirus disease (COVID-19) on the management and outcomes of acute stroke. We conducted a systematic review and meta-analysis to evaluate the aforementioned considerations. We performed a meta-analysis of observational cohort studies reporting on the occurrence and/or outcomes of patients with cerebrovascular events in association with their SARS-CoV-2 infection status. We used a random-effects model. Summary estimates were reported as odds ratios (ORs) and corresponding 95% confidence intervals (CIs). We identified 18 cohort studies including 67,845 patients. Among patients with SARS-CoV-2, 1.3% (95% CI = 0.9-1.6%, I SARS-CoV-2 appears to be associated with an increased risk of ischemic stroke, and potentially cryptogenic stroke in particular. It may also be related to an increased mortality risk. ANN NEUROL 2021;89:380-388.

Identifiants

pubmed: 33219563
doi: 10.1002/ana.25967
pmc: PMC7753413
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

380-388

Informations de copyright

© 2020 American Neurological Association.

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Auteurs

Aristeidis H Katsanos (AH)

Division of Neurology, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada.
Second Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Lina Palaiodimou (L)

Second Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Ramin Zand (R)

Neuroscience Institute, Geisinger Health System, Danville, PA.

Shadi Yaghi (S)

Department of Neurology, NYU Langone Health, New York, NY.

Hooman Kamel (H)

Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY.

Babak B Navi (BB)

Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY.

Guillaume Turc (G)

Department of Neurology, Paris Psychiatry and Neurosciences University Hospital Group, Sainte Anne Hospital, Paris, France.
University of Paris, Paris, France.
INSERM U1266, Paris, France.
FHU Neurovasc, Paris, France.

Michele Romoli (M)

Neurology Unit, Maurizio Bufalini Hospital, Cesena, Italy.
Neurology Clinic, University of Perugia-S. Maria del la Misericordia Hospital, Perugia, Italy.

Vijay K Sharma (VK)

Division of Neurology, Department of Medicine, National University Hospital, Singapore and School of Medicine, National University of Singapore, Singapore.

Dimitris Mavridis (D)

Department of Primary Education, University of Ioannina, Ioannina, Greece.
Faculty of Medicine, Paris Descartes University, Paris, France.

Shima Shahjouei (S)

Neuroscience Institute, Geisinger Health System, Danville, PA.

Luciana Catanese (L)

Division of Neurology, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada.

Ashkan Shoamanesh (A)

Division of Neurology, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada.

Konstantinos Vadikolias (K)

Department of Neurology, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Konstantinos Tsioufis (K)

First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece.

Pagona Lagiou (P)

Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA.

Andrei V Alexandrov (AV)

Department of Neurology, University of Tennessee Health Science Center, Memphis, TN.

Sotirios Tsiodras (S)

Fourth Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
National Public Health Organization of Greece, Athens, Greece.

Georgios Tsivgoulis (G)

Second Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Department of Neurology, University of Tennessee Health Science Center, Memphis, TN.

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