Are diabetes and its medications risk factors for the development of COVID-19? Data from a population-based study in Sicily.


Journal

Nutrition, metabolism, and cardiovascular diseases : NMCD
ISSN: 1590-3729
Titre abrégé: Nutr Metab Cardiovasc Dis
Pays: Netherlands
ID NLM: 9111474

Informations de publication

Date de publication:
08 02 2021
Historique:
received: 20 06 2020
revised: 23 09 2020
accepted: 23 09 2020
pubmed: 24 11 2020
medline: 25 2 2021
entrez: 23 11 2020
Statut: ppublish

Résumé

Diabetes mellitus (DM) has been associated with higher incidence of severe cases of COVID-19 in hospitalized patients, but it is unknown whether DM is a risk factor for the overall COVID-19 incidence. The aim of present study was to investigate whether there is an association of DM with COVID-19 prevalence and case fatality, and between different DM medications and risk for COVID-19 infection and death. retrospective observational study on all SARS-CoV-2 positive (SARS-CoV-2 in Sicily, DM was not a risk factor for COVID-19 infection, whereas it was associated with a higher case fatality.

Sections du résumé

BACKGROUND AND AIMS
Diabetes mellitus (DM) has been associated with higher incidence of severe cases of COVID-19 in hospitalized patients, but it is unknown whether DM is a risk factor for the overall COVID-19 incidence. The aim of present study was to investigate whether there is an association of DM with COVID-19 prevalence and case fatality, and between different DM medications and risk for COVID-19 infection and death.
METHODS AND RESULTS
retrospective observational study on all SARS-CoV-2 positive (SARS-CoV-2
CONCLUSIONS
in Sicily, DM was not a risk factor for COVID-19 infection, whereas it was associated with a higher case fatality.

Identifiants

pubmed: 33223405
pii: S0939-4753(20)30415-4
doi: 10.1016/j.numecd.2020.09.028
pmc: PMC7528967
pii:
doi:

Substances chimiques

Hypoglycemic Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

396-398

Informations de copyright

Copyright © 2020 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Références

J Endocrinol Invest. 2020 Jun;43(6):867-869
pubmed: 32222956
Diabetes Res Clin Pract. 2020 Apr;162:108125
pubmed: 32224164
BMJ. 2020 Mar 26;368:m1198
pubmed: 32217618
N Engl J Med. 2020 Aug 20;383(8):789-790
pubmed: 32530585
Diabetes Res Clin Pract. 2020 Apr;162:108137
pubmed: 32259611
N Engl J Med. 2020 Jun 18;382(25):2431-2440
pubmed: 32356627
Nutr Metab Cardiovasc Dis. 2020 Jul 24;30(8):1236-1248
pubmed: 32571616
Diabetes Obes Metab. 2020 Oct;22(10):1946-1950
pubmed: 32463179
J Gerontol A Biol Sci Med Sci. 2020 Sep 16;75(9):1796-1800
pubmed: 32506122
Diabetes Metab Syndr. 2020 Jul - Aug;14(4):303-310
pubmed: 32298981

Auteurs

G Antonio Silverii (GA)

Experimental and Clinical Biomedical Sciences "Mario Serio" Department, University of Florence, Italy. Electronic address: antonio.silverii@gmail.com.

Matteo Monami (M)

Experimental and Clinical Biomedical Sciences "Mario Serio" Department, University of Florence, Italy.

Achille Cernigliaro (A)

Health Activities and Epidemiologic Observatory Division, Health Department, Sicily Region, Italy.

Enrica Vigneri (E)

Health Promotion, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", PROMISE, University of Palermo, Italy.

Valentina Guarnotta (V)

Health Promotion, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", PROMISE, University of Palermo, Italy.

Salvatore Scondotto (S)

Health Activities and Epidemiologic Observatory Division, Health Department, Sicily Region, Italy.

Vincenza A Allotta (VA)

Health Activities and Epidemiologic Observatory Division, Health Department, Sicily Region, Italy.

Michela Conti (M)

Health Promotion, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", PROMISE, University of Palermo, Italy.

Carla Giordano (C)

Health Promotion, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", PROMISE, University of Palermo, Italy.

Edoardo Mannucci (E)

Experimental and Clinical Biomedical Sciences "Mario Serio" Department, University of Florence, Italy.

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Classifications MeSH