The increasing importance of


Journal

Infectious diseases (London, England)
ISSN: 2374-4243
Titre abrégé: Infect Dis (Lond)
Pays: England
ID NLM: 101650235

Informations de publication

Date de publication:
Feb 2021
Historique:
pubmed: 25 11 2020
medline: 1 6 2021
entrez: 24 11 2020
Statut: ppublish

Résumé

Numerous studies have shown that the aetiology of community-acquired pneumonia (CAP) varies considerably among different healthcare settings. Because empiric therapies for CAP should cover the major pathogens, reports examining CAP aetiology are considered crucial, particularly in Nordic countries that still rely on penicillin G or V treatments for most patients with CAP. The primary objective of our study was to report CAP aetiology. Secondary objectives included the estimation of positivity rates for different tests and the odds of a positive test for various subgroups. In this cohort study, microbiological data were analysed for an overall cohort (variable degree of microbiological testing) and for a subgroup that was tested for both, bacteria, viruses and fungi, using routine methods (defined as extensive testing). The overall cohort comprised 2,264 patients, including 315 who were extensively tested. Bacterial and viral monoinfections were the most commonly identified infections. The dominant pathogen identified among extensively tested patients was Our study indicated that

Sections du résumé

BACKGROUND BACKGROUND
Numerous studies have shown that the aetiology of community-acquired pneumonia (CAP) varies considerably among different healthcare settings. Because empiric therapies for CAP should cover the major pathogens, reports examining CAP aetiology are considered crucial, particularly in Nordic countries that still rely on penicillin G or V treatments for most patients with CAP. The primary objective of our study was to report CAP aetiology. Secondary objectives included the estimation of positivity rates for different tests and the odds of a positive test for various subgroups.
METHODS METHODS
In this cohort study, microbiological data were analysed for an overall cohort (variable degree of microbiological testing) and for a subgroup that was tested for both, bacteria, viruses and fungi, using routine methods (defined as extensive testing).
RESULTS RESULTS
The overall cohort comprised 2,264 patients, including 315 who were extensively tested. Bacterial and viral monoinfections were the most commonly identified infections. The dominant pathogen identified among extensively tested patients was
CONCLUSION CONCLUSIONS
Our study indicated that

Identifiants

pubmed: 33231116
doi: 10.1080/23744235.2020.1846776
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

122-130

Auteurs

Markus Fally (M)

Department of Internal Medicine, Section for Pulmonary Diseases, Herlev Gentofte Hospital, Hellerup, Denmark.

Simone Israelsen (S)

Department of Infectious Diseases, Amager Hvidovre Hospital, Hvidovre, Denmark.

Jacob Anhøj (J)

Centre of Diagnostic Investigation, Rigshospitalet, Copenhagen, Denmark.

Thomas Benfield (T)

Department of Infectious Diseases, Amager Hvidovre Hospital, Hvidovre, Denmark.

Britta Tarp (B)

Diagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.

Lilian Kolte (L)

Department of Respiratory Medicine and Infectious Diseases, Nordsjællands Hospital, Hillerød, Denmark.

Pernille Ravn (P)

Supervisor Department of Internal Medicine, Section for Infectious Diseases, Herlev Gentofte Hospital, Hellerup, Denmark.

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Classifications MeSH