Health service use among Manitobans with alcohol use disorder: a population-based matched cohort study.


Journal

CMAJ open
ISSN: 2291-0026
Titre abrégé: CMAJ Open
Pays: Canada
ID NLM: 101620603

Informations de publication

Date de publication:
Historique:
entrez: 25 11 2020
pubmed: 26 11 2020
medline: 26 11 2020
Statut: epublish

Résumé

Alcohol is the drug most commonly used by Canadians, with multiple impacts on health and health service use. We examined patterns of short- and long-term health service use among people with a diagnosis of alcohol use disorder. In this retrospective matched cohort study, we used population-based administrative data from the province of Manitoba, Canada, to identify individuals aged 12 years or older with a first indication of alcohol use disorder (index date) in the period 1990 to 2015. We matched cases (those with diagnosis of alcohol use disorder) to controls (those without this diagnosis), at a 1:5 ratio, on the basis of age, sex, geographic region and income quintile at the index date. The outcome measures were inpatient hospital admission, outpatient physician visits, emergency department visits and use of prescription medications. We modelled crude rates using generalized estimating equations with either a negative binomial or a Poisson distribution RESULTS: We identified 53 410 people with alcohol use disorder and 264 857 matched controls. All outcomes occurred at a higher rate among people with the disorder than among controls. For example, during the year of diagnosis, the rate ratio for hospital admission was 4.0 (95% confidence interval [CI] 3.9-4.2) for women and 4.5 (95% CI 4.4-4.7) for men. All rates of health service use peaked close to the index date, but remained significantly higher among people with alcohol use disorder than among controls for 20 years. Among people with alcohol use disorder, the most commonly filled prescriptions were for psycholeptics, whereas among controls, the most commonly filled prescriptions were for sex hormones (women) and antihypertensives (men). Compared with controls, people with alcohol use disorder used significantly more health services from the time of diagnosis and over the next 20 years. This finding highlights the need for better detection and early intervention to reduce the need for acute and emergency care, as well as the need for improved management of alcohol use disorder over the longer term.

Sections du résumé

BACKGROUND
Alcohol is the drug most commonly used by Canadians, with multiple impacts on health and health service use. We examined patterns of short- and long-term health service use among people with a diagnosis of alcohol use disorder.
METHODS
In this retrospective matched cohort study, we used population-based administrative data from the province of Manitoba, Canada, to identify individuals aged 12 years or older with a first indication of alcohol use disorder (index date) in the period 1990 to 2015. We matched cases (those with diagnosis of alcohol use disorder) to controls (those without this diagnosis), at a 1:5 ratio, on the basis of age, sex, geographic region and income quintile at the index date. The outcome measures were inpatient hospital admission, outpatient physician visits, emergency department visits and use of prescription medications. We modelled crude rates using generalized estimating equations with either a negative binomial or a Poisson distribution RESULTS: We identified 53 410 people with alcohol use disorder and 264 857 matched controls. All outcomes occurred at a higher rate among people with the disorder than among controls. For example, during the year of diagnosis, the rate ratio for hospital admission was 4.0 (95% confidence interval [CI] 3.9-4.2) for women and 4.5 (95% CI 4.4-4.7) for men. All rates of health service use peaked close to the index date, but remained significantly higher among people with alcohol use disorder than among controls for 20 years. Among people with alcohol use disorder, the most commonly filled prescriptions were for psycholeptics, whereas among controls, the most commonly filled prescriptions were for sex hormones (women) and antihypertensives (men).
INTERPRETATION
Compared with controls, people with alcohol use disorder used significantly more health services from the time of diagnosis and over the next 20 years. This finding highlights the need for better detection and early intervention to reduce the need for acute and emergency care, as well as the need for improved management of alcohol use disorder over the longer term.

Identifiants

pubmed: 33234583
pii: 8/4/E762
doi: 10.9778/cmajo.20200124
pmc: PMC7721253
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

E762-E771

Informations de copyright

Copyright 2020, Joule Inc. or its licensors.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

James M Bolton (JM)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Christine Leong (C)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Okechukwu Ekuma (O)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Heather J Prior (HJ)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Geoffrey Konrad (G)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Jennifer Enns (J)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Deepa Singal (D)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Josh Nepon (J)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Michael T Paillé (MT)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Greg Finlayson (G)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.

Nathan C Nickel (NC)

Department of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man. Nathan_Nickel@umanitoba.ca.

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