The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
11 2020
Historique:
received: 13 06 2020
accepted: 07 10 2020
entrez: 26 11 2020
pubmed: 27 11 2020
medline: 27 11 2020
Statut: epublish

Résumé

Frameshift mutations in

Identifiants

pubmed: 33239297
pii: 6/48/eabd3139
doi: 10.1126/sciadv.abd3139
pmc: PMC7688335
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Medical Research Council
ID : MC_UU_00014/2
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_12009
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 206328/Z/17/Z
Pays : United Kingdom
Organisme : Blood Cancer UK
ID : 18002
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M008975/1
Pays : United Kingdom

Informations de copyright

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

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Auteurs

Daniel Prins (D)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Department of Haematology, University of Cambridge, Cambridge, UK.

Hyun Jung Park (HJ)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Department of Haematology, University of Cambridge, Cambridge, UK.

Sam Watcham (S)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Department of Haematology, University of Cambridge, Cambridge, UK.

Juan Li (J)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Department of Haematology, University of Cambridge, Cambridge, UK.

Michele Vacca (M)

Wellcome Trust-Medical Research Council Institute of Metabolic Science-Metabolic Research Laboratories, Addenbrooke's Hospital, Cambridge, UK.

Hugo P Bastos (HP)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Department of Haematology, University of Cambridge, Cambridge, UK.

Alexander Gerbaulet (A)

Institute for Immunology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

Antonio Vidal-Puig (A)

Wellcome Trust-Medical Research Council Institute of Metabolic Science-Metabolic Research Laboratories, Addenbrooke's Hospital, Cambridge, UK.
Wellcome Trust Sanger Institute, Hinxton, UK.

Berthold Göttgens (B)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Department of Haematology, University of Cambridge, Cambridge, UK.

Anthony R Green (AR)

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. arg1000@cam.ac.uk.
Department of Haematology, University of Cambridge, Cambridge, UK.

Classifications MeSH