Ischial tuberosity: new donor site for bone grafts in animal cleft research.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
26 11 2020
26 11 2020
Historique:
received:
16
08
2020
accepted:
17
11
2020
entrez:
27
11
2020
pubmed:
28
11
2020
medline:
19
3
2021
Statut:
epublish
Résumé
In the context of cleft repair in animal research in rat models, different areas can be used for bone grafting. The aim of the present study was to present the tuberosity of the ischium as a new donor site and to evaluate its quality in relation to an artificial alveolar cleft. Four weeks after creating experimental alveolar clefts in seven Wistar rats, the repair was performed in the now twelve-week-old male animals using bone blocks grafted from the ischial tuberosity. Two days before surgery and two as well as twenty-eight days after surgery, microCT scans were performed, and the grafted bone blocks were analyzed regarding height, width, thickness, and volume. Additionally, bone mineral density (BMD) and bone volume fraction (BV/TV) were measured in the repaired cleft. The mean bone volume of the graft was about 19.77 ± 7.77mm
Identifiants
pubmed: 33244089
doi: 10.1038/s41598-020-77862-w
pii: 10.1038/s41598-020-77862-w
pmc: PMC7691372
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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