Lack of almagate interference in breath test results for Helicobacter pylori diagnosis (Almatest study).
Ausencia de interferencia de almagato en los resultados de la prueba de aliento para el diagnóstico de Helicobacter pylori (estudio Almatest).
Aluminum Hydroxide
/ administration & dosage
Antacids
/ administration & dosage
Breath Tests
/ methods
Carbon Isotopes
Carbonates
/ administration & dosage
Dyspepsia
/ drug therapy
False Negative Reactions
Female
Gastroesophageal Reflux
/ drug therapy
Helicobacter Infections
/ diagnosis
Helicobacter pylori
Humans
Magnesium Hydroxide
/ administration & dosage
Male
Middle Aged
Spain
Time Factors
Urea
Almagate
Almagato
Antacids
Antiácidos
Dispepsia
Dyspepsia
Helicobacter pylori
TAU
Test de aliento de urea
UBT
Urea breath test
Journal
Gastroenterologia y hepatologia
ISSN: 0210-5705
Titre abrégé: Gastroenterol Hepatol
Pays: Spain
ID NLM: 8406671
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
09
07
2020
revised:
05
10
2020
accepted:
22
10
2020
pubmed:
29
11
2020
medline:
4
2
2022
entrez:
28
11
2020
Statut:
ppublish
Résumé
The Observational, multicentre study in adult patients treated with almagate in whom a UBT (TAUKIT®) was indicated. When the UBT result was negative, use of almagate was stopped for 30 days and the UBT was repeated. When the result was positive, no further determinations were made. The primary endpoint was the percentage of patients who, having had a negative result in the first breath test, were positive in the second after having stopped taking almagate (UBT false negatives, possibly attributable to almagate). Of the 167 evaluable patients, 59% were female, average age was 49 and 97% had gastrointestinal symptoms. The result of the first UBT was negative in 71% of cases. Of these, in the second UBT test after stopping the almagate, the negative result was confirmed in 97.5%. Out of the total number of cases evaluated, the rate of false negatives was 1.8%. Taking almagate has minimal or no interference in the result of UBT for the diagnosis of H. pylori infection. It can therefore be used in the weeks prior to a UBT.
Identifiants
pubmed: 33248174
pii: S0210-5705(20)30446-5
doi: 10.1016/j.gastrohep.2020.10.016
pii:
doi:
Substances chimiques
Antacids
0
Carbon Isotopes
0
Carbonates
0
almagate
568Z59H7ZJ
Aluminum Hydroxide
5QB0T2IUN0
Urea
8W8T17847W
Magnesium Hydroxide
NBZ3QY004S
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
spa
Sous-ensembles de citation
IM
Pagination
628-636Informations de copyright
Copyright © 2021 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.