Bio-mechanical characterization of a CAD/CAM PMMA resin for digital removable prostheses.
Apoptosis
Brillouin spectroscopy
CAD/CAM
Cytotoxicity
Dynamic Mechanical Analysis
PMMA
SEM
Journal
Dental materials : official publication of the Academy of Dental Materials
ISSN: 1879-0097
Titre abrégé: Dent Mater
Pays: England
ID NLM: 8508040
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
09
07
2020
revised:
15
10
2020
accepted:
06
11
2020
pubmed:
2
12
2020
medline:
24
4
2021
entrez:
1
12
2020
Statut:
ppublish
Résumé
To compare the mechanical and biological features of a polymethylmethacrylate (PMMA) disc for CAD/CAM prostheses (test samples, TG) with a traditional resin (control samples, CG). Mechanical analysis was performed using Dynamic Mechanical Analysis (DMA) and Brillouin's micro-spectroscopy. Human keratinocyte morphology and adhesion were analyzed by scanning electronic microscopy (SEM), cytotoxicity by the MTT assay, apoptosis by flow cytometry and p53, p21 and bcl2 gene expression by real time PCR. TG exhibited a higher elastic modulus than CG (range 5100-5500 ± 114.3 MPa vs 3000-3300 ± 99.97 MPa). The Brillouin frequency was found at ω PMMA resins, as used in CAD/CAM technology, displayed suitable biocompatible and mechanical properties for removable prostheses.
Identifiants
pubmed: 33257084
pii: S0109-5641(20)30310-9
doi: 10.1016/j.dental.2020.11.003
pii:
doi:
Substances chimiques
Dental Implants
0
Polymethyl Methacrylate
9011-14-7
Types de publication
Journal Article
Langues
eng
Pagination
e118-e130Informations de copyright
Copyright © 2020 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.