Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded

Bacterial Proteins Biofilms Crystallography, X-Ray Cytochrome b Group Ferredoxins Ferritins Pseudomonas aeruginosa
Pseudomonas aeruginosa bacterioferritin biofilm iron homeostasis iron metabolism

Journal

ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580

Informations de publication

Date de publication:
08 01 2021
Historique:
pubmed: 4 12 2020
medline: 24 6 2021
entrez: 3 12 2020
Statut: ppublish

Résumé

Bacteria depend on a well-regulated iron homeostasis to survive adverse environments. A key component of the iron homeostasis machinery is the compartmentalization of Fe

Identifiants

DOI: 10.1021/acsinfecdis.0c00669 PMID: 33269912 PMC: PMC7802073
pubmed: 33269912
doi: 10.1021/acsinfecdis.0c00669
pmc: PMC7802073
doi:

Substances chimiques

Bacterial Proteins 0
Cytochrome b Group 0
Ferredoxins 0
Ferritins 9007-73-2
bacterioferritin 9035-38-5

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

123-140

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI125529
Pays : United States

Références

Antimicrob Agents Chemother. 2013 May;57(5):2432-3
pubmed: 23580579
Metallomics. 2017 Jun 21;9(6):646-659
pubmed: 28318006
FEMS Microbiol Rev. 2010 Jul;34(4):415-25
pubmed: 20059548
Infect Immun. 1980 May;28(2):546-56
pubmed: 6772562
Pharm Stat. 2011 Mar-Apr;10(2):128-34
pubmed: 22328315
Adv Exp Med Biol. 2019;1145:1-8
pubmed: 31364067
Curr Opin Infect Dis. 2009 Dec;22(6):535-43
pubmed: 19797945
Lancet. 2001 Jul 14;358(9276):135-8
pubmed: 11463434
Antimicrob Agents Chemother. 1992 Jun;36(6):1208-14
pubmed: 1416820
J Bacteriol. 2007 Jan;189(1):28-37
pubmed: 17041046
Biochemistry. 2011 Jun 14;50(23):5236-48
pubmed: 21574546
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):282-92
pubmed: 21460446
J Med Chem. 2016 Jul 28;59(14):6929-42
pubmed: 27353344
Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14440-14475
pubmed: 29939462
Org Prep Proced Int. 2018;50(3):372-374
pubmed: 30559532
Int J Antimicrob Agents. 2010 Apr;35(4):322-32
pubmed: 20149602
Biochemistry. 2018 Sep 25;57(38):5533-5543
pubmed: 30183257
J Clin Invest. 2007 Apr;117(4):877-88
pubmed: 17364024
J Am Chem Soc. 2019 May 22;141(20):8171-8184
pubmed: 31038945
Lancet Infect Dis. 2006 Sep;6(9):589-601
pubmed: 16931410
Biochemistry. 2009 Aug 11;48(31):7420-31
pubmed: 19575528
Acta Crystallogr D Biol Crystallogr. 2010 Jan;66(Pt 1):12-21
pubmed: 20057044
Microbiology (Reading). 2000 Oct;146 ( Pt 10):2395-2407
pubmed: 11021916
FEMS Immunol Med Microbiol. 2005 Mar 1;43(3):325-30
pubmed: 15708305
Medchemcomm. 2019 Mar 21;10(4):505-512
pubmed: 31057729
Trends Microbiol. 2015 Jan;23(1):7-13
pubmed: 25449050
Clin Oral Investig. 2013 Apr;17(3):841-50
pubmed: 22821430
J Clin Microbiol. 2019 Mar 28;57(4):
pubmed: 30541939
Biomedicines. 2019 Apr 30;7(2):
pubmed: 31052335
ACS Infect Dis. 2018 Jul 13;4(7):1041-1047
pubmed: 29771109
Trends Microbiol. 2019 Oct;27(10):850-863
pubmed: 31178124
Wound Repair Regen. 2008 Jan-Feb;16(1):37-44
pubmed: 18086294
Antimicrob Agents Chemother. 1997 Jun;41(6):1352-8
pubmed: 9174198
Antimicrob Agents Chemother. 2003 Jan;47(1):317-23
pubmed: 12499208
Am J Respir Cell Mol Biol. 2009 Sep;41(3):305-13
pubmed: 19168700
Angew Chem Int Ed Engl. 2016 Jun 1;55(23):6600-26
pubmed: 27000559
J Pediatr. 2007 Aug;151(2):134-9, 139.e1
pubmed: 17643762
Sci Transl Med. 2018 Sep 26;10(460):
pubmed: 30257953
J Intern Med. 2012 Dec;272(6):541-61
pubmed: 23025745
Microbiology (Reading). 2001 Jan;147(Pt 1):3-9
pubmed: 11160795
J Antimicrob Chemother. 2001 Jul;48 Suppl 1:5-16
pubmed: 11420333
Antimicrob Agents Chemother. 1990 Sep;34(9):1666-71
pubmed: 2126686
Antimicrob Agents Chemother. 2003 Apr;47(4):1251-6
pubmed: 12654654
Nat Rev Microbiol. 2016 Apr;14(5):320-30
pubmed: 27080241
Appl Environ Microbiol. 2006 Mar;72(3):2064-9
pubmed: 16517655
Biochemistry. 2010 Feb 16;49(6):1160-75
pubmed: 20067302
Antibiotics (Basel). 2020 Mar 27;9(4):
pubmed: 32230813
EMBO J. 2003 Aug 1;22(15):3803-15
pubmed: 12881415
Mol Microbiol. 2004 Feb;51(3):675-90
pubmed: 14731271
J Med Microbiol. 2009 Jun;58(Pt 6):765-773
pubmed: 19429753
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Acc Chem Res. 2017 Feb 21;50(2):331-340
pubmed: 28177216
Future Microbiol. 2014;9(3):379-97
pubmed: 24762310
Nature. 2000 Aug 31;406(6799):959-64
pubmed: 10984043
J Am Chem Soc. 2012 Jun 20;134(24):9898-901
pubmed: 22656303
ACS Infect Dis. 2020 Mar 13;6(3):447-458
pubmed: 31898890
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21
pubmed: 20124702
Nucleic Acids Res. 2019 Jul 2;47(W1):W636-W641
pubmed: 30976793
FEMS Immunol Med Microbiol. 2010 Aug;59(3):253-68
pubmed: 20497222
Clin Infect Dis. 2009 Jan 1;48(1):1-12
pubmed: 19035777
BMC Pulm Med. 2016 Dec 7;16(1):176
pubmed: 27927212
ACS Infect Dis. 2020 Aug 14;6(8):2073-2085
pubmed: 32551497
Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11076-81
pubmed: 16043697
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):293-302
pubmed: 21460447
Lancet Infect Dis. 2018 Mar;18(3):318-327
pubmed: 29276051
Nucleic Acids Res. 2016 Jan 4;44(D1):D646-53
pubmed: 26578582
Environ Microbiol. 2013 Jun;15(6):1661-73
pubmed: 23126435
J Clin Microbiol. 1999 Jun;37(6):1771-6
pubmed: 10325322
Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13635-40
pubmed: 8942986
Biotechnol Rep (Amst). 2015 Jun 23;7:120-127
pubmed: 28626721
Nature. 2002 May 30;417(6888):552-5
pubmed: 12037568
J Microbiol. 2018 Jul;56(7):449-457
pubmed: 29948830
Nat Rev Drug Discov. 2003 Feb;2(2):114-22
pubmed: 12563302
Appl Environ Microbiol. 2004 Oct;70(10):6188-96
pubmed: 15466566
J Am Chem Soc. 2012 Aug 15;134(32):13470-81
pubmed: 22812654
J Bacteriol. 1991 Oct;173(20):6558-67
pubmed: 1917879
J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674
pubmed: 19461840
FEMS Microbiol Ecol. 2011 Jul;77(1):83-94
pubmed: 21395624
Pathog Dis. 2016 Feb;74(1):ftv086
pubmed: 26458402
Science. 1999 May 21;284(5418):1318-22
pubmed: 10334980
Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W5-9
pubmed: 18440982
Annu Rev Microbiol. 2003;57:677-701
pubmed: 14527295
Lett Appl Microbiol. 2019 Apr;68(4):350-359
pubmed: 30740751
J Med Chem. 2018 May 10;61(9):3845-3854
pubmed: 29554424
Biochim Biophys Acta. 2009 Jul;1790(7):600-5
pubmed: 18675317
J Antimicrob Chemother. 2005 Oct;56(4):665-71
pubmed: 16105852
Biochemistry. 2015 Oct 13;54(40):6162-75
pubmed: 26368531
Ann Intern Med. 1987 Nov;107(5):678-80
pubmed: 3662280
Front Chem. 2019 Nov 28;7:824
pubmed: 31850313
Appl Environ Microbiol. 1998 Oct;64(10):4035-9
pubmed: 9758837
Mol Microbiol. 2008 Apr;68(1):223-40
pubmed: 18312276

Auteurs

Anabel Soldano (A)

Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, Louisiana 70803, United States.

Huili Yao (H)

Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, Louisiana 70803, United States.

Achala N D Punchi Hewage (AND)

Department of Chemistry, University of Kansas, 2030 Becker Drive, Lawrence, Kansas 66047, United States.

Kevin Meraz (K)

Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.

Joel K Annor-Gyamfi (JK)

Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.

Richard A Bunce (RA)

Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.

Kevin P Battaile (KP)

NYX, New York Structural Biology Center, Upton, New York 11973, United States.
ORCID: 0000-0003-0833-3259

Scott Lovell (S)

Protein Structure Laboratory, University of Kansas, 2034 Becker Drive, Lawrence, Kansas 66047, United States.

Mario Rivera (M)

Department of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, Louisiana 70803, United States.
ORCID: 0000-0002-5692-5497

Articles similaires

Atomic view of photosynthetic metabolite permeability pathways and confinement in synthetic carboxysome shells.

Daipayan Sarkar, Christopher Maffeo, Markus Sutter et al.
1.00
Photosynthesis Ribulose-Bisphosphate Carboxylase Carbon Dioxide Molecular Dynamics Simulation Cyanobacteria

Menthol as an effective inhibitor of quorum sensing and biofilm formation in Candida albicans and Candida glabrata by targeting the transcriptional repressor TUP1.

Pouria Khodavandi, Maryam Miri Soogh, Fahimeh Alizadeh et al.
1.00
Biofilms Candida albicans Quorum Sensing Candida glabrata Menthol

Bioinspired gelated cell sheet-supported lactobacillus biofilm for aerobic vaginitis diagnosis and treatment.

Yueyue Gui, Qingfei Sun, Kexin Li et al.
1.00
Female Biofilms Animals Lactobacillus Mice

Two codependent routes lead to high-level MRSA.

Abimbola Feyisara Adedeji-Olulana, Katarzyna Wacnik, Lucia Lafage et al.
1.00
Methicillin-Resistant Staphylococcus aureus Penicillin-Binding Proteins Peptidoglycan Bacterial Proteins Anti-Bacterial Agents

Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Small Molecule Inhibitors of the...
questionsmedicales.fr › Phénomènes microbiologiques › Biofilms › Small Molecule Inhibitors of the...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Small Molecule Inhibitors of the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochromes de type b › Small Molecule Inhibitors of the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines végétales › Ferrédoxines › Small Molecule Inhibitors of the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Métalloprotéines › Protéines de liaison au fer › Ferritines › Small Molecule Inhibitors of the...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa › Small Molecule Inhibitors of the...