Assessing the biological potential of new symmetrical ferrocene based bisthiourea analogues.
Anti-Infective Agents
/ chemical synthesis
Bacteria
/ drug effects
Catalytic Domain
Density Functional Theory
Drug Design
Ferrous Compounds
/ chemical synthesis
Fungi
/ drug effects
Glycoside Hydrolase Inhibitors
/ chemical synthesis
Humans
Hypoglycemic Agents
/ chemical synthesis
Metallocenes
/ chemical synthesis
Microbial Sensitivity Tests
Models, Chemical
Molecular Docking Simulation
Molecular Structure
Protein Binding
Structure-Activity Relationship
Thiourea
/ analogs & derivatives
alpha-Amylases
/ antagonists & inhibitors
alpha-Glucosidases
/ chemistry
Antidiabetic compounds
Biological applications
Bisferrocenyl bisthiourea
DPPH scavenging
Hydrogen atom transfer mechanism
Journal
Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
15
06
2020
revised:
26
07
2020
accepted:
02
08
2020
pubmed:
6
12
2020
medline:
4
9
2021
entrez:
5
12
2020
Statut:
ppublish
Résumé
In the present work synthesis and characterization of five new bisferrocenyl bisthiourea analogues (G
Identifiants
pubmed: 33276979
pii: S0045-2068(20)31477-2
doi: 10.1016/j.bioorg.2020.104180
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Ferrous Compounds
0
Glycoside Hydrolase Inhibitors
0
Hypoglycemic Agents
0
Metallocenes
0
alpha-Amylases
EC 3.2.1.1
alpha-Glucosidases
EC 3.2.1.20
Thiourea
GYV9AM2QAG
ferrocene
U96PKG90JQ
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
104180Informations de copyright
Copyright © 2020. Published by Elsevier Inc.