Association of Vegetation Size With Valve Destruction, Embolism and Mortality.


Journal

Heart, lung & circulation
ISSN: 1444-2892
Titre abrégé: Heart Lung Circ
Pays: Australia
ID NLM: 100963739

Informations de publication

Date de publication:
Jun 2021
Historique:
received: 23 06 2020
revised: 09 09 2020
accepted: 03 10 2020
pubmed: 7 12 2020
medline: 22 9 2021
entrez: 6 12 2020
Statut: ppublish

Résumé

The mortality of patients with infective endocarditis (IE) is high. The management of patients with large vegetations is controversial. This study sought to investigate the association of vegetation size on outcomes including valve destruction, embolism and mortality. One hundred and forty-two (142) patients with definite IE and transoesophageal echocardiography (TEE) imaging available for analysis were identified and data retrospectively reviewed. Vegetation length, width and area were measured. Severe valve destruction was defined as the composite of one or more of severe valve regurgitation, abscess, pseudoaneurysm, perforation or fistula. Associations with 6-month mortality were identified by Cox regression analysis. Eighty (80) (56.3%) patients had evidence of valve destruction on TEE. Vegetation length ≥10 mm and vegetation area ≥50 mm Vegetation length ≥10 mm or area ≥50 mm

Identifiants

pubmed: 33279409
pii: S1443-9506(20)31520-1
doi: 10.1016/j.hlc.2020.10.028
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

854-860

Subventions

Organisme : Medical Research Council
ID : MR/R017468/1
Pays : United Kingdom

Informations de copyright

Copyright © 2020 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

Auteurs

William J Young (WJ)

Echocardiography Laboratory, Barts Heart Centre, St Bartholomew's Hospital, London, UK; Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK; William Harvey Research Institute, Queen Mary University of London, London, UK.

David Hoare (D)

Echocardiography Laboratory, Barts Heart Centre, St Bartholomew's Hospital, London, UK; Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Innocent Bvekerwa (I)

Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Christopher Primus (C)

Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK; William Harvey Research Institute, Queen Mary University of London, London, UK.

Robert Serafino Wani (RS)

Department of Microbiology, St Bartholomew's Hospital, London, UK.

Satya Das (S)

Department of Microbiology, St Bartholomew's Hospital, London, UK.

Kit Wong (K)

Department of Cardiac Surgery, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Rakesh Uppal (R)

William Harvey Research Institute, Queen Mary University of London, London, UK; Department of Cardiac Surgery, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Martin Thomas (M)

Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Ceri Davies (C)

Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Guy Lloyd (G)

Echocardiography Laboratory, Barts Heart Centre, St Bartholomew's Hospital, London, UK; Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK; William Harvey Research Institute, Queen Mary University of London, London, UK.

Simon Woldman (S)

Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK; William Harvey Research Institute, Queen Mary University of London, London, UK.

Sanjeev Bhattacharyya (S)

Echocardiography Laboratory, Barts Heart Centre, St Bartholomew's Hospital, London, UK; Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, UK; William Harvey Research Institute, Queen Mary University of London, London, UK. Electronic address: Sanjeev.Bhattacharyya@nhs.net.

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Classifications MeSH