Clinical and molecular characterization of the R751L-CFTR mutation.


Journal

American journal of physiology. Lung cellular and molecular physiology
ISSN: 1522-1504
Titre abrégé: Am J Physiol Lung Cell Mol Physiol
Pays: United States
ID NLM: 100901229

Informations de publication

Date de publication:
01 02 2021
Historique:
pubmed: 10 12 2020
medline: 24 3 2021
entrez: 9 12 2020
Statut: ppublish

Résumé

Cystic fibrosis (CF) arises from mutations in the CF transmembrane conductance regulator (

Identifiants

pubmed: 33296276
doi: 10.1152/ajplung.00137.2020
pmc: PMC8476205
doi:

Substances chimiques

CFTR protein, human 0
Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6
Sodium Chloride 451W47IQ8X

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

L288-L300

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M008797/1
Pays : United Kingdom
Organisme : Medical Research Council (MRC)
ID : MR/M008797/1
Organisme : Wellcome Trust (Wellcome)
ID : 203520/Z/16/Z

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Auteurs

Iram J Haq (IJ)

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Paediatric Respiratory Medicine, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

Mike Althaus (M)

Institute for Functional Gene Analytics, Department of Natural Sciences, Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany.

Aaron Ions Gardner (AI)

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Hui Ying Yeoh (HY)

Cellular Protein Chemistry, Science4Life, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Urjita Joshi (U)

Cellular Protein Chemistry, Science4Life, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Vinciane Saint-Criq (V)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Bernard Verdon (B)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Jennifer Townshend (J)

Paediatric Respiratory Medicine, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

Christopher O'Brien (C)

Paediatric Respiratory Medicine, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

Mahfud Ben-Hamida (M)

Department of Paediatrics, West Cumberland Hospital, Whitehaven, United Kingdom.

Matthew Thomas (M)

Paediatric Respiratory Medicine, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

Stephen Bourke (S)

Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.

Peter van der Sluijs (P)

Cellular Protein Chemistry, Science4Life, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Ineke Braakman (I)

Cellular Protein Chemistry, Science4Life, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Chris Ward (C)

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Michael A Gray (MA)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Malcolm Brodlie (M)

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Paediatric Respiratory Medicine, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

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Classifications MeSH