A Highly Specific Assay for the Detection of SARS-CoV-2-Reactive CD4
Journal
Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R
Informations de publication
Date de publication:
01 02 2021
01 02 2021
Historique:
received:
09
07
2020
accepted:
16
11
2020
pubmed:
11
12
2020
medline:
30
1
2021
entrez:
10
12
2020
Statut:
ppublish
Résumé
Gaining detailed insights into the role of host immune responses in viral clearance is critical for understanding COVID-19 pathogenesis and future treatment strategies. Although studies analyzing humoral immune responses against SARS-CoV-2 were available rather early during the pandemic, cellular immunity came into focus of investigations just recently. For the present work, we have adapted a protocol designed for the detection of rare neoantigen-specific memory T cells in cancer patients for studying cellular immune responses against SARS-CoV-2. Both CD4
Identifiants
pubmed: 33298615
pii: jimmunol.2000811
doi: 10.4049/jimmunol.2000811
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
580-587Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 by The American Association of Immunologists, Inc.