Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Alleles
Animals
B-Lymphocytes
/ metabolism
Cell Self Renewal
Cell Transformation, Neoplastic
/ genetics
Chromatin
/ chemistry
Chromatin Assembly and Disassembly
/ genetics
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Gene Silencing
Genes, Tumor Suppressor
Germinal Center
/ pathology
Histones
/ deficiency
Humans
Lymphoma
/ genetics
Mice
Mutation
Stem Cells
/ metabolism
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
02
01
2020
accepted:
08
10
2020
pubmed:
11
12
2020
medline:
26
2
2021
entrez:
10
12
2020
Statut:
ppublish
Résumé
Linker histone H1 proteins bind to nucleosomes and facilitate chromatin compaction
Identifiants
pubmed: 33299181
doi: 10.1038/s41586-020-3017-y
pii: 10.1038/s41586-020-3017-y
pmc: PMC7855728
mid: NIHMS1636448
doi:
Substances chimiques
Chromatin
0
Histones
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
299-305Subventions
Organisme : NCI NIH HHS
ID : R01 CA252239
Pays : United States
Organisme : NCI NIH HHS
ID : P01 CA196539
Pays : United States
Organisme : NIGMS NIH HHS
ID : P41 GM108569
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA060553
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM138386
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA195732
Pays : United States
Organisme : NIH HHS
ID : S10 OD025194
Pays : United States
Organisme : NCI NIH HHS
ID : U54 CA193419
Pays : United States
Organisme : NCI NIH HHS
ID : R35 CA220499
Pays : United States
Organisme : NCI NIH HHS
ID : P01 CA229086
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM122562
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA228528
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM116143
Pays : United States
Organisme : NIGMS NIH HHS
ID : R44 GM116584
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA234561
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA194547
Pays : United States
Organisme : NIDCR NIH HHS
ID : R44 DE029633
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA260028
Pays : United States
Commentaires et corrections
Type : CommentIn
Références
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