Epidemiological characteristics of COVID-19 cases and estimates of the reproductive numbers 1 month into the epidemic, Italy, 28 January to 31 March 2020.


Journal

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452

Informations de publication

Date de publication:
12 2020
Historique:
entrez: 11 12 2020
pubmed: 12 12 2020
medline: 2 1 2021
Statut: ppublish

Résumé

BackgroundOn 20 February 2020, a locally acquired coronavirus disease (COVID-19) case was detected in Lombardy, Italy. This was the first signal of ongoing transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the country. The number of cases in Italy increased rapidly and the country became the first in Europe to experience a SARS-CoV-2 outbreak.AimOur aim was to describe the epidemiology and transmission dynamics of the first COVID-19 cases in Italy amid ongoing control measures.MethodsWe analysed all RT-PCR-confirmed COVID-19 cases reported to the national integrated surveillance system until 31 March 2020. We provide a descriptive epidemiological summary and estimate the basic and net reproductive numbers by region.ResultsOf the 98,716 cases of COVID-19 analysed, 9,512 were healthcare workers. Of the 10,943 reported COVID-19-associated deaths (crude case fatality ratio: 11.1%) 49.5% occurred in cases older than 80 years. Male sex and age were independent risk factors for COVID-19 death. Estimates of R

Identifiants

pubmed: 33303064
doi: 10.2807/1560-7917.ES.2020.25.49.2000790
pmc: PMC7730489
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Investigateurs

Angela di Martino (A)
Marzia Facchini (M)
Stefania Giannitelli (S)
Fabiola Mancini (F)
Simona Puzelli (S)
Roberta Urciuoli (R)
Antonia Petrucci (A)
Michele Labianca (M)
Anna Domenica Mignuoli (AD)
Angelo D'Argenzio (A)
Erika Massimiliani (E)
Tolinda Gallo (T)
Paola Scognamiglio (P)
Camilla Sticchi (C)
Danilo Cereda (D)
Daniel Fiacchini (D)
Francesco Sforza (F)
Maria Grazia Zuccaro (MG)
Pier Paolo Benetollo (PP)
Donatella Tiberti (D)
Maria Chironna (M)
Maria Antonietta Palmas (MA)
Salvatore Scondotto (S)
Emanuela Balocchini (E)
Anna Tosti (A)
Mauro Ruffier (M)
Filippo Da Re (F)

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Auteurs

Flavia Riccardo (F)

Istituto Superiore di Sanità, Rome, Italy.
These authors contributed equally.

Marco Ajelli (M)

These authors contributed equally.
Bruno Kessler Foundation, Trento, Italy.
Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, United States.
Laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, United States.

Xanthi D Andrianou (XD)

Istituto Superiore di Sanità, Rome, Italy.
Cyprus University of Technology, Limassol, Cyprus.

Antonino Bella (A)

Istituto Superiore di Sanità, Rome, Italy.

Martina Del Manso (M)

Istituto Superiore di Sanità, Rome, Italy.
European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

Massimo Fabiani (M)

Istituto Superiore di Sanità, Rome, Italy.

Stefania Bellino (S)

Istituto Superiore di Sanità, Rome, Italy.

Stefano Boros (S)

Istituto Superiore di Sanità, Rome, Italy.

Alberto Mateo Urdiales (AM)

Istituto Superiore di Sanità, Rome, Italy.
European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

Valentina Marziano (V)

Bruno Kessler Foundation, Trento, Italy.

Maria Cristina Rota (MC)

Istituto Superiore di Sanità, Rome, Italy.

Antonietta Filia (A)

Istituto Superiore di Sanità, Rome, Italy.

Fortunato D'Ancona (F)

Istituto Superiore di Sanità, Rome, Italy.

Andrea Siddu (A)

Istituto Superiore di Sanità, Rome, Italy.

Ornella Punzo (O)

Istituto Superiore di Sanità, Rome, Italy.

Filippo Trentini (F)

Bruno Kessler Foundation, Trento, Italy.

Giorgio Guzzetta (G)

Bruno Kessler Foundation, Trento, Italy.

Piero Poletti (P)

Bruno Kessler Foundation, Trento, Italy.

Paola Stefanelli (P)

Istituto Superiore di Sanità, Rome, Italy.

Maria Rita Castrucci (MR)

Istituto Superiore di Sanità, Rome, Italy.

Alessandra Ciervo (A)

Istituto Superiore di Sanità, Rome, Italy.

Corrado Di Benedetto (C)

Istituto Superiore di Sanità, Rome, Italy.

Marco Tallon (M)

Istituto Superiore di Sanità, Rome, Italy.

Andrea Piccioli (A)

Istituto Superiore di Sanità, Rome, Italy.

Silvio Brusaferro (S)

Istituto Superiore di Sanità, Rome, Italy.

Giovanni Rezza (G)

Istituto Superiore di Sanità, Rome, Italy.

Stefano Merler (S)

Bruno Kessler Foundation, Trento, Italy.

Patrizio Pezzotti (P)

Istituto Superiore di Sanità, Rome, Italy.
The members of the COVID-19 working group are listed under Investigators.

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