Neurodegeneration in Hepatic and Neurologic Wilson's Disease.
Adolescent
Adult
Atrophy
/ diagnosis
Basal Ganglia
/ diagnostic imaging
Cerebellum
/ diagnostic imaging
Cohort Studies
Female
Hepatolenticular Degeneration
/ complications
Hippocampus
/ diagnostic imaging
Humans
Liver
/ pathology
Magnetic Resonance Imaging
Male
Nucleus Accumbens
/ diagnostic imaging
Young Adult
Journal
Hepatology (Baltimore, Md.)
ISSN: 1527-3350
Titre abrégé: Hepatology
Pays: United States
ID NLM: 8302946
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
revised:
23
11
2020
received:
16
06
2020
accepted:
02
12
2020
pubmed:
15
12
2020
medline:
6
1
2022
entrez:
14
12
2020
Statut:
ppublish
Résumé
Clinical presentation of Wilson disease (WD) includes hepatic and neurologic manifestations. This study compares subcortical brain regions by magnetic resonance imaging in patients with WD and without neurological symptoms. Distinct atrophy affecting the basal ganglia, accumbens, and hippocampus was present in neurological WD. Cerebellar atrophy was observed in hepatic WD without neurological symptoms.
Identifiants
pubmed: 33316133
doi: 10.1002/hep.31681
pmc: PMC8453945
pii: 01515467-202108000-00041
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1117-1120Informations de copyright
© 2020 The Authors. Hepatology published by Wiley Periodicals LLC on behalf of American Association for the Study of Liver Diseases.
Références
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