Cyanobacteria and Eukaryotic Microalgae as Emerging Sources of Antibacterial Peptides.
Algal Proteins
/ chemistry
Animals
Anti-Bacterial Agents
/ chemistry
Anti-Inflammatory Agents, Non-Steroidal
/ chemistry
Antihypertensive Agents
/ chemistry
Antimicrobial Cationic Peptides
/ chemistry
Antineoplastic Agents
/ chemistry
Bacterial Proteins
/ chemistry
Cyanobacteria
/ chemistry
Drug Synergism
Eukaryota
/ chemistry
Humans
Microalgae
/ chemistry
Solid-Phase Synthesis Techniques
antibacterial activity
antimicrobial
bioactive compounds
cyanobacteria
microalgae
peptide
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
09 Dec 2020
09 Dec 2020
Historique:
received:
30
10
2020
revised:
03
12
2020
accepted:
07
12
2020
entrez:
15
12
2020
pubmed:
16
12
2020
medline:
4
9
2021
Statut:
epublish
Résumé
Cyanobacteria and microalgae are oxygen-producing photosynthetic unicellular organisms encompassing a great diversity of species, which are able to grow under all types of extreme environments and exposed to a wide variety of predators and microbial pathogens. The antibacterial compounds described for these organisms include alkaloids, fatty acids, indoles, macrolides, peptides, phenols, pigments and terpenes, among others. This review presents an overview of antibacterial peptides isolated from cyanobacteria and microalgae, as well as their synergism and mechanisms of action described so far. Antibacterial cyanopeptides belong to different orders, but mainly from Oscillatoriales and Nostocales. Cyanopeptides have different structures but are mainly cyclic peptides. This vast peptide repertoire includes ribosomal and abundant non-ribosomal peptides, evaluated by standard conventional methodologies against pathogenic Gram-negative and Gram-positive bacteria. The antibacterial activity described for microalgal peptides is considerably scarcer, and limited to protein hydrolysates from two
Identifiants
pubmed: 33316949
pii: molecules25245804
doi: 10.3390/molecules25245804
pmc: PMC7763478
pii:
doi:
Substances chimiques
Algal Proteins
0
Anti-Bacterial Agents
0
Anti-Inflammatory Agents, Non-Steroidal
0
Antihypertensive Agents
0
Antimicrobial Cationic Peptides
0
Antineoplastic Agents
0
Bacterial Proteins
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Fondo Nacional de Desarrollo Científico y Tecnológico
ID : 1170379
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