Comprehension of computer code relies primarily on domain-general executive brain regions.


Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
15 12 2020
Historique:
received: 15 05 2020
accepted: 06 11 2020
entrez: 15 12 2020
pubmed: 16 12 2020
medline: 18 3 2021
Statut: epublish

Résumé

Computer programming is a novel cognitive tool that has transformed modern society. What cognitive and neural mechanisms support this skill? Here, we used functional magnetic resonance imaging to investigate two candidate brain systems: the multiple demand (MD) system, typically recruited during math, logic, problem solving, and executive tasks, and the language system, typically recruited during linguistic processing. We examined MD and language system responses to code written in Python, a text-based programming language (Experiment 1) and in ScratchJr, a graphical programming language (Experiment 2); for both, we contrasted responses to code problems with responses to content-matched sentence problems. We found that the MD system exhibited strong bilateral responses to code in both experiments, whereas the language system responded strongly to sentence problems, but weakly or not at all to code problems. Thus, the MD system supports the use of novel cognitive tools even when the input is structurally similar to natural language.

Identifiants

pubmed: 33319744
doi: 10.7554/eLife.58906
pii: 58906
pmc: PMC7738192
doi:
pii:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Science Foundation
ID : #1744809
Pays : International

Informations de copyright

© 2020, Ivanova et al.

Déclaration de conflit d'intérêts

AI, SS, YS, HK, RD, UO, MB, EF No competing interests declared

Références

J Cogn Neurosci. 2010 Jan;22(1):48-66
pubmed: 19199416
J Neurosci. 2017 Oct 11;37(41):9999-10011
pubmed: 28871034
Neuroimage. 2011 May 15;56(2):744-52
pubmed: 20406690
Trends Neurosci. 2000 Oct;23(10):475-83
pubmed: 11006464
Cereb Cortex. 2001 Mar;11(3):223-37
pubmed: 11230094
Elife. 2020 Dec 15;9:
pubmed: 33319744
Nat Rev Neurosci. 2002 Mar;3(3):243-9
pubmed: 11994756
Hum Brain Mapp. 2008 May;29(5):581-93
pubmed: 17557297
J Mol Graph Model. 1999 Feb;17(1):57-61
pubmed: 10660911
Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3519-24
pubmed: 15713804
Nat Commun. 2016 Jul 18;7:12141
pubmed: 27424918
Trends Cogn Sci. 2014 Mar;18(3):120-6
pubmed: 24440115
Neuroimage. 2012 May 1;60(4):2357-64
pubmed: 22398396
J Neurophysiol. 2018 Nov 1;120(5):2555-2570
pubmed: 30156457
Ann N Y Acad Sci. 2014 May;1316:87-104
pubmed: 24697242
Neuropsychol Rev. 2002 Dec;12(4):179-231
pubmed: 12539968
Neuropsychologia. 2000;38(10):1426-40
pubmed: 10869586
J Cogn Neurosci. 2020 Jul;32(7):1348-1368
pubmed: 32108555
Science. 2002 Nov 22;298(5598):1569-79
pubmed: 12446899
J Neurosci. 2010 Sep 22;30(38):12581-8
pubmed: 20861364
Annu Rev Psychol. 2012;63:511-37
pubmed: 21943170
Neuroimage. 2012 Nov 15;63(3):1646-69
pubmed: 22784644
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16428-33
pubmed: 21885736
Lang Cogn Neurosci. 2016;31(4):567-574
pubmed: 27525290
Neuropsychologia. 2009 Mar;47(4):1107-16
pubmed: 19166867
J Neurophysiol. 2010 Aug;104(2):1177-94
pubmed: 20410363
J Neurosci. 2011 Feb 23;31(8):2906-15
pubmed: 21414912
Cereb Cortex. 2009 Dec;19(12):2767-96
pubmed: 19329570
Neuropsychologia. 2019 Sep;132:107132
pubmed: 31276684
J Neurosci. 2011 Mar 9;31(10):3843-52
pubmed: 21389239
Front Hum Neurosci. 2015 Aug 06;9:430
pubmed: 26300757
Nat Neurosci. 2018 Apr;21(4):474-483
pubmed: 29507407
Neuroimage. 2006 May 1;30(4):1088-96; discussion 1097-9
pubmed: 16635578
Elife. 2020 Dec 15;9:
pubmed: 33319745
Neuropsychologia. 1989;27(5):607-17
pubmed: 2739887
Trends Cogn Sci. 2006 Feb;10(2):59-63
pubmed: 16406760
Annu Rev Linguist. 2015;1:377-394
pubmed: 28642932
J Neurosci. 1996 Aug 15;16(16):5154-67
pubmed: 8756444
J Neurosci. 2013 Oct 2;33(40):15978-88
pubmed: 24089502
Neuroimage. 2019 Apr 1;189:19-31
pubmed: 30611876
Psychol Sci. 2012 Aug 1;23(8):914-22
pubmed: 22760883
Cognition. 2020 Oct;203:104348
pubmed: 32569894
Arch Neurol. 1994 Mar;51(3):286-91
pubmed: 8129641
Neuropsychologia. 2020 Feb 17;138:107307
pubmed: 31874149
Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16616-21
pubmed: 24062451
Neuroimage. 2012 Jan 16;59(2):1369-81
pubmed: 21875671
Brain Cogn. 2003 Nov;53(2):171-6
pubmed: 14607141
Neuron. 2013 Oct 2;80(1):35-50
pubmed: 24094101
Neuron. 2004 Oct 28;44(3):557-69
pubmed: 15504334
Neuroimage. 2007 Sep 1;37(3):1005-16
pubmed: 17627851
Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12554-9
pubmed: 19617569
Neuroimage. 2016 Feb 1;126:39-48
pubmed: 26589334
J Neurophysiol. 2019 Apr 1;121(4):1244-1265
pubmed: 30601693
Sci Rep. 2020 Mar 2;10(1):3817
pubmed: 32123206
Brain Imaging Behav. 2019 Jun;13(3):623-637
pubmed: 29744802
Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5072-81
pubmed: 27503892
J Neurosci. 2019 Sep 25;39(39):7722-7736
pubmed: 31427396
J Neurophysiol. 2019 Apr 1;121(4):1513-1534
pubmed: 30785825
Trends Cogn Sci. 2015 Jun;19(6):304-13
pubmed: 25980649
Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11163-70
pubmed: 20484679
Proc Natl Acad Sci U S A. 2016 May 3;113(18):4909-17
pubmed: 27071124
Neuron. 2011 Dec 8;72(5):692-7
pubmed: 22153367
Neuropsychologia. 2001;39(11):1224-39
pubmed: 11527560
J Neurosci. 2016 Aug 17;36(33):8574-85
pubmed: 27535906
Cognition. 2005 Sep;97(2):179-210; discussion 211-25
pubmed: 16112662
Neuroimage. 2020 Oct 1;219:116925
pubmed: 32407994
Science. 2001 Jan 12;291(5502):312-6
pubmed: 11209083
Neuropsychologia. 2003;41(14):1942-58
pubmed: 14572527
Neuropsychologia. 2018 Oct;119:501-511
pubmed: 30243926
Cereb Cortex. 2019 Jun 1;29(6):2396-2411
pubmed: 29771323
Cereb Cortex. 2012 Jul;22(7):1593-603
pubmed: 21893681
Brain Cogn. 1991 Nov;17(2):102-15
pubmed: 1799448
Annu Rev Neurosci. 2001;24:167-202
pubmed: 11283309
Trends Cogn Sci. 2010 Apr;14(4):172-9
pubmed: 20171926
Neuroimage. 2016 Oct 1;139:74-93
pubmed: 27261158
Wiley Interdiscip Rev Cogn Sci. 2011 Sep;2(5):461-478
pubmed: 26302300
Cogn Neurosci. 2017 Jul;8(3):167-176
pubmed: 27386919
Neuropsychologia. 2012 Mar;50(4):499-513
pubmed: 21945850
Trends Cogn Sci. 2013 Feb;17(2):89-98
pubmed: 23313359
Trends Cogn Sci. 2007 Oct;11(10):435-41
pubmed: 17913567
Perspect Psychol Sci. 2013 Jan;8(1):108-13
pubmed: 23544033
Curr Biol. 2000 Jun 15;10(12):723-6
pubmed: 10873809
J Neurophysiol. 2014 Sep 1;112(5):1105-18
pubmed: 24872535
Cogn Psychol. 1997 Jun;33(1):43-63
pubmed: 9212721
Neuron. 2004 Mar 25;41(6):983-93
pubmed: 15046729
Trends Cogn Sci. 2019 Jul;23(7):525-528
pubmed: 31153775
Cogn Neuropsychol. 2017 Sep;34(6):377-393
pubmed: 29188746
Trends Cogn Sci. 2020 Apr;24(4):270-284
pubmed: 32160565
Lang Cogn Neurosci. 2020;35(6):780-796
pubmed: 32984430
Nat Hum Behav. 2018 Mar;2(3):200-204
pubmed: 31620646
Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21219-21227
pubmed: 31570622
Neuropsychologia. 2001;39(9):901-9
pubmed: 11516443
Elife. 2015 Apr 13;4:e06481
pubmed: 25866927
eNeuro. 2020 Dec 11;:
pubmed: 33318072
Neurosci Lett. 2005 Jan 20;373(3):212-7
pubmed: 15619545
J Neurophysiol. 2020 Nov 1;124(5):1415-1448
pubmed: 32965153
Nat Commun. 2019 May 2;10(1):2027
pubmed: 31048694
Neuron. 2015 Aug 19;87(4):882-92
pubmed: 26291168
J Neurosci. 2020 Jun 3;40(23):4536-4550
pubmed: 32317387
Annu Rev Neurosci. 2004;27:369-92
pubmed: 15217337
Cereb Cortex. 2020 Jun 30;30(8):4361-4380
pubmed: 32244253
Soc Neurosci. 2006;1(3-4):334-48
pubmed: 18633798
J Neurosci. 2018 Nov 7;38(45):9689-9699
pubmed: 30249790
Nat Commun. 2018 Mar 6;9(1):963
pubmed: 29511192
J Cogn Neurosci. 2019 Nov;31(11):1617-1630
pubmed: 31274390

Auteurs

Anna A Ivanova (AA)

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, United States.
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, United States.

Shashank Srikant (S)

Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, United States.

Yotaro Sueoka (Y)

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, United States.
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, United States.

Hope H Kean (HH)

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, United States.
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, United States.

Riva Dhamala (R)

Eliot-Pearson Department of Child Study and Human Development, Tufts University, Medford, United States.

Una-May O'Reilly (UM)

Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, United States.

Marina U Bers (MU)

Eliot-Pearson Department of Child Study and Human Development, Tufts University, Medford, United States.

Evelina Fedorenko (E)

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, United States.
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, United States.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH