Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material.
C. albicans
PMMA
antifungal
chitosan
chitosan glutamate
chitosan-HCl
denture base
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
13 Dec 2020
13 Dec 2020
Historique:
received:
26
11
2020
revised:
04
12
2020
accepted:
07
12
2020
entrez:
16
12
2020
pubmed:
17
12
2020
medline:
15
4
2021
Statut:
epublish
Résumé
Chitosan (CS) and its derivatives show antimicrobial properties. This is of interest in preventing and treating denture stomatitis, which can be caused by fungi. Therefore, the aim of this study was the development of a novel antifungal denture base material by modifying polymethyl methacrylate (PMMA) with CS-salt and characterizing its antifungal and surface properties in vitro. For this purpose, the antifungal effect of chitosan-hydrochloride (CS-HCl) or chitosan-glutamate (CS-G) as solutions in different concentrations was determined. To obtain modified PMMA resin specimens, the CS-salts were added to the PMMA before polymerization. The roughness of these specimens was measured by contact profilometry. For the evaluation of the antifungal properties of the CS-salt modified resins, a
Identifiants
pubmed: 33322112
pii: molecules25245899
doi: 10.3390/molecules25245899
pmc: PMC7763281
pii:
doi:
Substances chimiques
Antifungal Agents
0
Salts
0
Polymethyl Methacrylate
9011-14-7
Chitosan
9012-76-4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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