Furan-Conjugated Tripeptides as Potent Antitumor Drugs.
3T3 Cells
Amides
Animals
Antineoplastic Agents
/ chemistry
Apoptosis
/ drug effects
Cell Line, Tumor
Cell Proliferation
Cell Survival
/ drug effects
Doxorubicin
/ pharmacology
Drug Screening Assays, Antitumor
Endothelial Cells
/ drug effects
Female
Furans
/ chemistry
HeLa Cells
Human Umbilical Vein Endothelial Cells
Humans
Inhibitory Concentration 50
MCF-7 Cells
Magnetic Resonance Spectroscopy
Mice
Microscopy, Atomic Force
Peptides
/ chemistry
Protein Domains
Uterine Cervical Neoplasms
/ drug therapy
HeLa cell line
Rink amide resin
anticancer
furan-based tripeptides
heterocycles
peptide conjugates
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
16 12 2020
16 12 2020
Historique:
received:
08
11
2020
revised:
10
12
2020
accepted:
12
12
2020
entrez:
19
12
2020
pubmed:
20
12
2020
medline:
14
9
2021
Statut:
epublish
Résumé
Cervical cancer is among the leading causes of death in women. Chemotherapy options available for cervical cancer include highly cytotoxic drugs such as taxol, cisplatin, 5-florouracil, and doxorubicin, which are not specific. In the current study, we have identified a new peptide conjugate (Fur
Identifiants
pubmed: 33339257
pii: biom10121684
doi: 10.3390/biom10121684
pmc: PMC7766758
pii:
doi:
Substances chimiques
Amides
0
Antineoplastic Agents
0
Furans
0
Peptides
0
Doxorubicin
80168379AG
furan
UC0XV6A8N9
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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