Healthcare Costs, School Performance, and Health-related Quality of Life in Adolescence Following Psychotic Experiences in Preadolescence: A Longitudinal Cohort Study.


Journal

Schizophrenia bulletin
ISSN: 1745-1701
Titre abrégé: Schizophr Bull
Pays: United States
ID NLM: 0236760

Informations de publication

Date de publication:
29 04 2021
Historique:
pubmed: 22 12 2020
medline: 23 11 2021
entrez: 21 12 2020
Statut: ppublish

Résumé

Psychotic experiences (PEs) are common in the general population in preadolescence. The implications of PEs on socioeconomic outcomes, including educational attainment, are scarcely described. We aimed to estimate how preadolescent PEs were associated with later healthcare costs, school performance, and health-related quality of life (HRQoL) in adolescence. A total of 1607 preadolescents from the general population Copenhagen Child Cohort 2000 were assessed for PEs at age 11-12 years and followed up over 5 years using register-based data on mental and somatic healthcare costs, and school performance at age 16. Furthermore, HRQoL was assessed for a subsample of the children at age 16-17. We adjusted for perinatal and family sociodemographic adversities, prior parental mental illness and healthcare use, child IQ-estimate at age 11-12, and parent-rated general psychopathology of their child. PEs were associated with slightly poorer school performance. However, preadolescents with PEs more often reported HRQoL within the lowest 10th percentile (OR = 2.74 [95% CI 1.71-4.37]). Preadolescents who reported PEs had higher average total healthcare costs over the following 5 years. The costs for individuals with PEs were higher for mental healthcare services across primary to tertiary care, but not for somatic care. After adjustments, PEs remained independently associated with higher costs and poorer HRQoL, but not with poorer school performance. In conclusion, PEs are important in mental health screening of preadolescents and identify a group of young people with increased healthcare service-use throughout adolescence and who report poorer HRQoL in adolescence, over and above parent-rated general psychopathology of their child.

Identifiants

pubmed: 33345286
pii: 6042488
doi: 10.1093/schbul/sbaa175
pmc: PMC8673435
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

682-691

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.All rights reserved. For permissions, please email: journals.permissions@oup.com.

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Auteurs

Martin Køster Rimvall (MK)

Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Rasmus Trap Wolf (RT)

Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, Denmark.
Department of Public Health, Danish Centre for Health Economics (DaCHE), University of Southern Denmark, Odense, Denmark.

Else Marie Olsen (EM)

Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Center for Clinical Research and Prevention, Capital Region of Denmark, Denmark.

Anne Mette Skovgaard (AM)

National Institute of Public Health, University of Southern Denmark, Odense, Denmark.

Lars Clemmensen (L)

Center for Telepsychiatry, Mental Health Services, Region of Southern Denmark, Odense, Denmark.
Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

Anne Sophie Oxholm (AS)

Department of Public Health, Danish Centre for Health Economics (DaCHE), University of Southern Denmark, Odense, Denmark.

Frank Verhulst (F)

Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Department of Child Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Charlotte Ulrikka Rask (CU)

Aarhus University Hospital, Department of Child and Adolescent Psychiatry, Research Unit, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Jim van Os (J)

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands.
Department of Psychiatry and Psychology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Department of Psychosis Studies, King's College London, King's Health Partners, Institute of Psychiatry, London, UK.

Pia Jeppesen (P)

Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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