Physiological roles of heteromerization: focus on the two-pore domain potassium channels.
K+ channels
diversity
gating
heteromerization
trafficking
Journal
The Journal of physiology
ISSN: 1469-7793
Titre abrégé: J Physiol
Pays: England
ID NLM: 0266262
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
01
10
2020
accepted:
07
12
2020
pubmed:
22
12
2020
medline:
21
4
2021
entrez:
21
12
2020
Statut:
ppublish
Résumé
Potassium channels form the largest family of ion channels with more than 80 members involved in cell excitability and signalling. Most of them exist as homomeric channels, whereas specific conditions are required to obtain heteromeric channels. It is well established that heteromerization of voltage-gated and inward rectifier potassium channels affects their function, increasing the diversity of the native potassium currents. For potassium channels with two pore domains (K
Substances chimiques
Potassium Channels, Tandem Pore Domain
0
Potassium
RWP5GA015D
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1041-1055Informations de copyright
© 2020 The Authors. The Journal of Physiology © 2020 The Physiological Society.
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