Reply to "Comment on López-Yerena et al. 'Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats'
bioavailability
extra virgin olive oil
in vivo study
metabolites
permeability
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
17 Dec 2020
17 Dec 2020
Historique:
received:
02
09
2020
revised:
11
11
2020
accepted:
11
11
2020
entrez:
22
12
2020
pubmed:
23
12
2020
medline:
23
12
2020
Statut:
epublish
Résumé
Recently, in February 2020, we published a study exploring the intestinal absorption and metabolism of oleocanthal (OLC) in rats. A single-pass intestinal perfusion technique (SPIP) was used, involving simultaneous sampling from the luminal perfusate and mesenteric blood. Later, comments on our published paper were released, requesting clarification of specific data. In this detailed reply, we hope to have addressed and clarified all the concerns of A. Kaddoumi and K. El Sayed and that the scientific community will benefit from both the study and the comments it has generated.
Identifiants
pubmed: 33348608
pii: pharmaceutics12121221
doi: 10.3390/pharmaceutics12121221
pmc: PMC7765908
pii:
doi:
Types de publication
Journal Article
Langues
eng
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