The error-related negativity as a neuromarker of risk or resilience in young children.
anxiety
cognitive control
emotion regulation
error-related negativity
executive functioning
Journal
Brain and behavior
ISSN: 2162-3279
Titre abrégé: Brain Behav
Pays: United States
ID NLM: 101570837
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
revised:
09
10
2020
received:
06
04
2020
accepted:
29
11
2020
pubmed:
24
12
2020
medline:
1
7
2021
entrez:
23
12
2020
Statut:
ppublish
Résumé
The error-related negativity (ERN) is a neural response that reflects error monitoring. Contradictorily, an enlarged (more negative) ERN has been cited as both a risk factor and a protective factor, which hinders its utility as a predictive indicator. The aim of the current study was to examine the associations between ERN measured in early childhood with the development of cognitive control (CC), emotion regulation, and internalizing/externalizing symptoms over 1-2 years. When children were ages 5-7, EEG was collected during a Go/No-Go task. A subset of the original participants (n = 30) were selected based on their baseline ERN in an extreme-case design: half with high-amplitude ERN, matched by age and sex with another group with low-amplitude ERN. At follow-up, children in the High-Amplitude group showed better executive function, less self-reported anxiety and depression, less affect dysregulation, more parent-rated CC, less lability/negativity, and fewer parent-reported externalizing problems. Many results held even when accounting for baseline levels. Further, emotion dysregulation mediated the relationship between the ERN and both anxiety and externalizing problems, while CC mediated the ERN's relationship with externalizing problems only. These results can inform identification and intervention efforts for children at risk for psychopathology.
Identifiants
pubmed: 33354942
doi: 10.1002/brb3.2008
pmc: PMC7994696
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e02008Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR000433
Pays : United States
Organisme : NIMH NIH HHS
ID : R03 MH102648
Pays : United States
Informations de copyright
© 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC.
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