BCG lymphadenitis: a potential complication of immune reconstitution following haematopoietic stem cell transplant.


Journal

Archives of disease in childhood. Education and practice edition
ISSN: 1743-0593
Titre abrégé: Arch Dis Child Educ Pract Ed
Pays: England
ID NLM: 101220684

Informations de publication

Date de publication:
08 2022
Historique:
received: 09 10 2020
accepted: 22 11 2020
pubmed: 24 12 2020
medline: 22 7 2022
entrez: 23 12 2020
Statut: ppublish

Résumé

An MHC class II deficient 2-year-old boy presented with fever and an enlarging left neck mass 100 days post allogeneic haematopoietic stem cell transplant (HSCT). Fever persisted despite treatment with broad-spectrum β-lactam antibiotics. His BCG vaccination site at presentation was quiescent. Ultrasound showed enlarged cervical lymph nodes. An incisional biopsy of the large nodal mass yielded acid-fast bacilli, identified as

Identifiants

pubmed: 33355234
pii: archdischild-2020-320883
doi: 10.1136/archdischild-2020-320883
doi:

Substances chimiques

BCG Vaccine 0
Isoniazid V83O1VOZ8L
Rifampin VJT6J7R4TR

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

274-275

Informations de copyright

© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Christo Tsilifis (C)

Paediatric Immunology and Infectious Diseases, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK c.tsilifis@nhs.net.
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.

Ina Schim van der Loeff (I)

Paediatric Immunology and Infectious Diseases, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.

Eleri Williams (E)

Paediatric Immunology and Infectious Diseases, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Stephen Owens (S)

Paediatric Immunology and Infectious Diseases, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Steven Powell (S)

Paediatric Otolaryngology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Andrew Gennery (A)

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.
Paediatric Haematopoietic Stem Cell Transplant Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Mary Slatter (M)

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.
Paediatric Haematopoietic Stem Cell Transplant Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

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Classifications MeSH