Brucellosis.
Brucellosis
Chronic meningitis
Meningo-encephalitis
Unpasteurized milk
Zoonosis
Journal
Journal of the neurological sciences
ISSN: 1878-5883
Titre abrégé: J Neurol Sci
Pays: Netherlands
ID NLM: 0375403
Informations de publication
Date de publication:
15 01 2021
15 01 2021
Historique:
received:
19
08
2020
revised:
05
11
2020
accepted:
17
12
2020
pubmed:
29
12
2020
medline:
15
5
2021
entrez:
28
12
2020
Statut:
ppublish
Résumé
Brucellosis is a common Zoonosis affecting half a million people annually. The most common mode of infection is by consuming unpasteurized milk or milk products. The general manifestations are those of fever with generalized symptoms. The nervous system is affected in 4-7% of cases. The manifestations are protean and include meningo-encephalitis as well as peripheral nervous system involvement. The diagnosis relies on culture, which is cumbersome and can be falsely negative. Agglutination tests for the various species of the organism are the mainstay for diagnosis. Treatment is for 3-6 months with combination therapy including Doxycycline, Rifampicin and ceftriaxone. The main issue is prevention and better animal husbandry.
Identifiants
pubmed: 33358192
pii: S0022-510X(20)30616-X
doi: 10.1016/j.jns.2020.117280
pii:
doi:
Substances chimiques
Doxycycline
N12000U13O
Rifampin
VJT6J7R4TR
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
117280Informations de copyright
Copyright © 2020. Published by Elsevier B.V.