Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
B-cell receptor
antigen
antigens of infectious origin
autoreactivity
lymphoma
posttransnational modification
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
09
2020
accepted:
02
11
2020
entrez:
28
12
2020
pubmed:
29
12
2020
medline:
29
12
2020
Statut:
epublish
Résumé
The B-cell receptor (BCR) signaling pathway is a crucial pathway of B cells, both for their survival and for antigen-mediated activation, proliferation and differentiation. Its activation is also critical for the genesis of many lymphoma types. BCR-mediated lymphoma proliferation may be caused by activating BCR-pathway mutations and/or by active or tonic stimulation of the BCR. BCRs of lymphomas have frequently been described as polyreactive. In this review, the role of specific target antigens of the BCRs of lymphomas is highlighted. These antigens have been found to be restricted to specific lymphoma entities. The antigens can be of infectious origin, such as
Identifiants
pubmed: 33363034
doi: 10.3389/fonc.2020.604685
pmc: PMC7756126
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
604685Informations de copyright
Copyright © 2020 Thurner, Hartmann, Neumann, Hoth, Stilgenbauer, Küppers, Preuss and Bewarder.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Science. 2014 Jan 10;343(6167):152-7
pubmed: 24310608
Nat Med. 2018 May;24(5):679-690
pubmed: 29713087
Leuk Lymphoma. 2015;56(10):2779-86
pubmed: 25726955
Blood. 2015 Jul 2;126(1):61-8
pubmed: 25972157
J Clin Invest. 2005 May;115(5):1352-60
pubmed: 15841210
Nature. 2012 Sep 13;489(7415):309-12
pubmed: 22885698
Arthritis Rheum. 2011 Feb;63(2):556-67
pubmed: 21280010
Acta Neuropathol. 2011 Dec;122(6):791-2
pubmed: 22020631
Blood. 1999 Sep 1;94(5):1738-46
pubmed: 10477699
Ann N Y Acad Sci. 2011 Dec;1246:102-7
pubmed: 22236434
Blood. 2011 Sep 22;118(12):3340-6
pubmed: 21791414
J Exp Med. 2013 Jan 14;210(1):59-70
pubmed: 23296468
Int J Cancer. 2009 Aug 1;125(3):656-61
pubmed: 19405124
Immunology. 1986 Nov;59(3):411-7
pubmed: 3491784
Nat Immunol. 2004 Mar;5(3):317-27
pubmed: 14758357
Lancet. 2016 Feb 20;387(10020):770-8
pubmed: 26673811
Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3507-14
pubmed: 16186327
Nature. 1988 Aug 25;334(6184):676-82
pubmed: 3261841
Cancer Discov. 2018 Oct;8(10):1300-1315
pubmed: 30093506
N Engl J Med. 2015 Apr 9;372(15):1430-40
pubmed: 25853747
Nat Rev Microbiol. 2005 Feb;3(2):182-7
pubmed: 15685227
Nat Genet. 2012 Dec;44(12):1316-20
pubmed: 23143595
Blood. 1999 Sep 15;94(6):1840-7
pubmed: 10477712
Clin Neuropathol. 2014 Jan-Feb;33(1):42-9
pubmed: 24359606
Blood. 2013 Jun 6;121(23):4708-17
pubmed: 23580660
Lancet. 1991 Nov 9;338(8776):1175-6
pubmed: 1682595
Nat Rev Drug Discov. 2018 May 30;17(6):385
pubmed: 29844593
Lancet. 2020 Apr 18;395(10232):1278-1291
pubmed: 32305093
Haematologica. 2020 Jul 16;:
pubmed: 32675228
Blood. 1990 Aug 1;76(3):562-9
pubmed: 2378986
Nature. 2000 Feb 3;403(6769):503-11
pubmed: 10676951
Blood. 2014 May 29;123(22):3398-405
pubmed: 24615778
Nat Rev Rheumatol. 2014 Oct;10(10):602-11
pubmed: 25003765
Hematol Oncol. 2011 Mar;29(1):31-7
pubmed: 20658474
Int J Cancer. 2015 Sep 1;137(5):1076-84
pubmed: 25677163
Blood. 2011 Mar 10;117(10):2918-23
pubmed: 21220746
N Engl J Med. 2018 Mar 29;378(13):1211-1223
pubmed: 29590547
Immunity. 1998 Sep;9(3):405-11
pubmed: 9768760
J Biol Chem. 1991 Jul 15;266(20):13364-9
pubmed: 1712782
N Engl J Med. 2013 Aug 8;369(6):507-16
pubmed: 23782157
Oncogene. 2001 Sep 10;20(40):5580-94
pubmed: 11607811
Cancer Cell. 2011 Dec 13;20(6):728-40
pubmed: 22137796
Curr Opin Immunol. 2015 Apr;33:70-7
pubmed: 25679954
Nature. 2018 Aug;560(7718):387-391
pubmed: 29925955
Blood. 1959 Oct;14:1151-8
pubmed: 13813891
Mol Immunol. 2008 Jun;45(11):3133-41
pubmed: 18430472
Blood. 2001 Dec 15;98(13):3745-9
pubmed: 11739181
Blood. 1997 Aug 1;90(3):1186-91
pubmed: 9242551
N Engl J Med. 2018 Apr 12;378(15):1396-1407
pubmed: 29641966
Blood. 2008 Apr 1;111(7):3838-48
pubmed: 18223168
Haematologica. 2008 May;93(5):697-705
pubmed: 18387977
Nature. 2000 Dec 7;408(6813):740-5
pubmed: 11130078
Nature. 2003 May 29;423(6939):506-11
pubmed: 12724780
Nature. 2004 Dec 2;432(7017):635-9
pubmed: 15577913
J Exp Med. 2000 Feb 21;191(4):603-12
pubmed: 10684852
EMBO J. 2018 Jun 1;37(11):
pubmed: 29669863
Nat Genet. 2008 Jan;40(1):108-12
pubmed: 18066064
JCI Insight. 2018 Apr 19;3(8):
pubmed: 29669929
J Exp Med. 2004 Aug 16;200(4):519-25
pubmed: 15314077
J Clin Invest. 2009 Jun;119(6):1668-77
pubmed: 19478457
J Clin Oncol. 2012 Aug 20;30(24):2988-94
pubmed: 22802315
J Exp Med. 2005 Mar 7;201(5):703-11
pubmed: 15738055
Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3161-5
pubmed: 7512726
Cancer Discov. 2017 Sep;7(9):1018-1029
pubmed: 28619981
Nature. 1996 Jun 27;381(6585):751-8
pubmed: 8657279
Blood. 2004 Nov 15;104(10):3312-7
pubmed: 15284115
Mol Med. 2008 Nov-Dec;14(11-12):665-74
pubmed: 19009014
Blood. 2012 Apr 5;119(14):3245-55
pubmed: 22337719
N Engl J Med. 2019 Aug 1;381(5):432-443
pubmed: 31365801
Haematologica. 2016 Sep;101(9):e378-81
pubmed: 27582571
PLoS Genet. 2008 Apr 25;4(4):e1000024
pubmed: 18437207
Nature. 2001 Jul 19;412(6844):341-6
pubmed: 11460166
Cancer Cell. 2016 Nov 14;30(5):806-821
pubmed: 27846393
Arthritis Rheum. 2000 Aug;43(8):1768-78
pubmed: 10943867
J Clin Invest. 2015 Jan;125(1):316-23
pubmed: 25485683
Nat Rev Immunol. 2006 Aug;6(8):573-83
pubmed: 16868548
Am J Pathol. 1991 Dec;139(6):1281-9
pubmed: 1721489
Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5413-7
pubmed: 2052620
J Neuroimmunol. 2008 Mar;195(1-2):28-35
pubmed: 18280586
Blood. 2018 May 31;131(22):2454-2465
pubmed: 29650799
Arthritis Rheum. 2000 Apr;43(4):908-16
pubmed: 10765938
Blood. 2013 Jan 3;121(1):239-41
pubmed: 23287626
Blood. 2010 Oct 28;116(17):3268-77
pubmed: 20628145
Science. 2016 Jul 8;353(6295):179-84
pubmed: 27365313
Blood. 2003 Oct 15;102(8):3003-9
pubmed: 12842981
N Engl J Med. 2002 Jul 11;347(2):89-94
pubmed: 12110736
J Proteome Res. 2011 Jan 7;10(1):105-12
pubmed: 20455595
Nat Rev Cancer. 2005 Apr;5(4):251-62
pubmed: 15803153
Science. 2003 Sep 5;301(5638):1374-7
pubmed: 12920303
Am J Pathol. 1983 Nov;113(2):181-97
pubmed: 6416075
Nat Immunol. 2004 Sep;5(9):943-52
pubmed: 15300245
Nat Commun. 2018 Jan 24;9(1):353
pubmed: 29367624
Hum Pathol. 2000 Feb;31(2):263-8
pubmed: 10685647
J Exp Med. 1997 Mar 3;185(5):843-54
pubmed: 9120390
N Engl J Med. 2011 Jun 16;364(24):2305-15
pubmed: 21663470
N Engl J Med. 2008 Nov 27;359(22):2313-23
pubmed: 19038878
Cell. 2001 Apr 20;105(2):177-86
pubmed: 11336668
Curr Opin Immunol. 2012 Feb;24(1):112-8
pubmed: 22209691
Nat Med. 2015 Aug;21(8):922-6
pubmed: 26193343
Nature. 1989 Feb 9;337(6207):562-6
pubmed: 2783762
Annu Rev Immunol. 2003;21:841-94
pubmed: 12615894
Cell. 2000 Sep 1;102(5):553-63
pubmed: 11007474
EMBO J. 1998 Mar 16;17(6):1700-9
pubmed: 9501091
N Engl J Med. 2014 Jul 17;371(3):213-23
pubmed: 24881631
Cancer Sci. 2011 Mar;102(3):565-8
pubmed: 21205072
Curr Opin Immunol. 2008 Dec;20(6):632-8
pubmed: 18848883
J Pathol. 2006 Jul;209(3):344-51
pubmed: 16583361
Blood. 2010 Jan 21;115(3):581-91
pubmed: 19965661
Proc Natl Acad Sci U S A. 2016 May 10;113(19):5376-81
pubmed: 27114517
Nature. 2009 Jun 4;459(7247):712-6
pubmed: 19412163
Nature. 1995 Jul 13;376(6536):181-4
pubmed: 7603571
Lancet. 1993 Sep 4;342(8871):575-7
pubmed: 8102719
N Engl J Med. 2010 Sep 30;363(14):1303-12
pubmed: 20879879
Eur J Immunol. 2011 Aug;41(8):2397-403
pubmed: 21604259
N Engl J Med. 1995 Nov 23;333(21):1374-9
pubmed: 7477117
Autoimmunity. 2006 Feb;39(1):31-9
pubmed: 16455580
PLoS One. 2010 Dec 30;5(12):e15992
pubmed: 21209908
Leuk Lymphoma. 2003;44 Suppl 3:S41-7
pubmed: 15202524
Blood. 2010 Sep 9;116(10):1818-9; author reply 1819-20
pubmed: 20829382
Nature. 2011 Feb 3;470(7332):115-9
pubmed: 21179087
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7415-9
pubmed: 6261256
J Clin Oncol. 2020 Sep 1;38(25):2849-2861
pubmed: 32459600
J Immunol. 2015 Aug 1;195(3):1312-9
pubmed: 26116512
Blood. 1990 Oct 1;76(7):1387-91
pubmed: 2207314
Immunity. 2008 Dec 19;29(6):912-21
pubmed: 19084434
N Engl J Med. 2012 Aug 30;367(9):826-33
pubmed: 22931316
J Biol Chem. 1992 May 5;267(13):9035-40
pubmed: 1374383
Blood. 2018 Dec 27;132(26):2744-2753
pubmed: 30249786
J Immunol. 2007 Oct 1;179(7):4704-10
pubmed: 17878369
Leuk Res. 2013 Apr;37(4):401-409
pubmed: 23347903
J Exp Med. 2009 May 11;206(5):981-9
pubmed: 19380639
Nature. 1991 Jan 24;349(6307):331-4
pubmed: 1898987
Br J Haematol. 2005 Oct;131(1):29-38
pubmed: 16173960
Blood. 2008 Dec 15;112(13):5122-9
pubmed: 18812466
Int J Cancer. 2009 Aug 1;125(3):639-48
pubmed: 19425054
N Engl J Med. 2016 Feb 11;374(6):555-61
pubmed: 26863356
Cell. 2017 Oct 5;171(2):481-494.e15
pubmed: 28985567
EMBO J. 2004 Sep 15;23(18):3689-99
pubmed: 15343266
Cell. 2015 Aug 13;162(4):727-37
pubmed: 26276629
Nature. 2011 Jun 05;475(7354):101-5
pubmed: 21642962
Immunity. 2010 Aug 27;33(2):181-91
pubmed: 20705491
Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10962-6
pubmed: 7971992
Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11816-21
pubmed: 9751748
Science. 1993 Aug 27;261(5125):1175-8
pubmed: 8356452
J Exp Med. 2005 Apr 18;201(8):1229-41
pubmed: 15837810
Blood. 2016 May 19;127(20):2375-90
pubmed: 26980727
Cell. 2012 Feb 17;148(4):739-51
pubmed: 22341446
Arthritis Res. 2000;2(4):249-51
pubmed: 11094435
Science. 1985 Sep 27;229(4720):1390-3
pubmed: 3929382
Proc Natl Acad Sci U S A. 1976 Oct;73(10):3628-32
pubmed: 824647
Nature. 2010 Jan 7;463(7277):88-92
pubmed: 20054396
N Engl J Med. 2002 Feb 21;346(8):564-9
pubmed: 11856795
Ann Oncol. 2016 Oct;27(10):1928-40
pubmed: 27672108
Blood. 2016 Sep 8;128(10):1362-73
pubmed: 27335277
Blood. 2011 Sep 15;118(11):3088-95
pubmed: 21791422
Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18587-92
pubmed: 20937880
Blood. 2016 Jul 7;128(1):82-92
pubmed: 27127301
J Autoimmun. 2011 Feb;36(1):87-90
pubmed: 20951001
J Exp Med. 2007 Jul 9;204(7):1583-93
pubmed: 17562816
J Exp Med. 2012 Aug 27;209(9):1537-51
pubmed: 22891273
Science. 2009 Sep 4;325(5945):1230-4
pubmed: 19729652
Nat Rev Immunol. 2001 Oct;1(1):75-82
pubmed: 11905817
Virchows Arch A Pathol Anat Histopathol. 1986;409(1):79-92
pubmed: 3085342
Nature. 2006 May 4;441(7089):106-10
pubmed: 16572121
J Proteome Res. 2010 Jun 4;9(6):2929-36
pubmed: 20433201
Nature. 2002 Apr 11;416(6881):603-7
pubmed: 11948342
Blood. 2003 May 15;101(10):4047-54
pubmed: 12637326
Int Immunol. 2003 Jul;15(7):789-96
pubmed: 12807817
N Engl J Med. 2014 Mar 13;370(11):997-1007
pubmed: 24450857
N Engl J Med. 2004 Jan 15;350(3):239-48
pubmed: 14724303
N Engl J Med. 2018 Jun 21;378(25):2399-2410
pubmed: 29856685
Leukemia. 2012 May;26(5):1127-31
pubmed: 22051533
J Biol Chem. 1991 Nov 5;266(31):21232-8
pubmed: 1718973
Blood. 2018 Jan 11;131(2):182-190
pubmed: 29074501
J Exp Med. 2007 Sep 3;204(9):2225-32
pubmed: 17724134
Ann Oncol. 2020 Jan;31(1):17-29
pubmed: 31912792
Science. 1990 Jun 22;248(4962):1517-23
pubmed: 2360047
J Biol Chem. 2008 Aug 15;283(33):22737-48
pubmed: 18499662
Blood. 2012 Jun 7;119(23):5359-66
pubmed: 22354002
Br J Haematol. 2019 Feb;184(3):384-391
pubmed: 30450574
J Exp Med. 1996 Oct 1;184(4):1495-505
pubmed: 8879220
Science. 2008 Mar 21;319(5870):1676-9
pubmed: 18323416
Adv Immunol. 2010;105:193-210
pubmed: 20510734
Nat Commun. 2019 Feb 18;10(1):820
pubmed: 30778055
J Immunol. 2009 Sep 1;183(5):2966-73
pubmed: 19667091
Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732):
pubmed: 28893938
Cell. 1996 Oct 18;87(2):319-29
pubmed: 8861915
Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11810-3
pubmed: 8524854
Blood. 2017 Feb 9;129(6):759-770
pubmed: 28011673
Annu Rev Immunol. 1994;12:117-39
pubmed: 8011279
Blood. 2007 Nov 15;110(10):3715-21
pubmed: 17682125
Am J Pathol. 1999 Dec;155(6):2077-86
pubmed: 10595937
Nature. 1986 Nov 20-26;324(6094):258-60
pubmed: 2431317
Eur J Immunol. 2007 Jul;37(7):1986-95
pubmed: 17523133
Immunity. 2003 Oct;19(4):607-20
pubmed: 14563324
Cell. 2000 Sep 1;102(5):565-75
pubmed: 11007475
Nat Immunol. 2004 Jun;5(6):645-50
pubmed: 15156139
Nat Commun. 2020 May 18;11(1):2465
pubmed: 32424289
Am J Surg Pathol. 2006 May;30(5):585-92
pubmed: 16699312
N Engl J Med. 1994 May 5;330(18):1267-71
pubmed: 8145781
J Clin Invest. 2005 Jun;115(6):1636-43
pubmed: 15902303
Lancet Oncol. 2010 Jan;11(1):12
pubmed: 20129126
Nat Genet. 2004 Apr;36(4):337-8
pubmed: 15004560
Science. 1993 Aug 27;261(5125):1171-5
pubmed: 8356451
Blood. 2010 May 13;115(19):3907-15
pubmed: 20110421
Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13447-54
pubmed: 26483459
Ann Oncol. 2015 Aug;26(8):1760-5
pubmed: 25935794
Nat Immunol. 2020 Sep;21(9):1082-1093
pubmed: 32601467
J Exp Med. 2005 May 16;201(10):1659-67
pubmed: 15897279
Blood. 2004 Jan 1;103(1):275-82
pubmed: 14504078
N Engl J Med. 2014 Jun 12;370(24):2286-94
pubmed: 24869598
J Clin Oncol. 2019 May 20;37(15):1285-1295
pubmed: 30901302
J Clin Invest. 1998 Jan 1;101(1):273-81
pubmed: 9421490
Leukemia. 2019 Jan;33(1):148-158
pubmed: 29955130
Nature. 1995 Apr 6;374(6522):546-9
pubmed: 7700380
Blood. 2007 Jan 1;109(1):259-70
pubmed: 16985177
Ann Intern Med. 1995 May 15;122(10):767-9
pubmed: 7717599
Blood. 2012 Mar 8;119(10):2293-301
pubmed: 22234695
Hum Immunol. 1992 Jun;34(2):135-41
pubmed: 1429034
Proc Natl Acad Sci U S A. 2016 May 17;113(20):5688-93
pubmed: 27155012
Acta Neuropathol. 2012 Dec;124(6):905-6
pubmed: 23138649
Blood. 2010 Apr 1;115(13):2578-85
pubmed: 19965662
Blood. 2004 Jul 15;104(2):543-9
pubmed: 15044251
PLoS One. 2011;6(6):e20991
pubmed: 21677771