Markus Hoth

Affiliations

Department of Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, 66421 Homburg, Germany.

Publications (30)

Deterministic actin waves as generators of cell polarization cues.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Luiza Stankevicins , Nicolas Ecker , Emmanuel Terriac , Paolo Maiuri , Rouven Schoppmeyer , Pablo Vargas , Ana-Maria Lennon-Duménil , Matthieu Piel , Bin Qu , Markus Hoth , Karsten Kruse , Franziska Lautenschläger

Calcium signal dynamics in T lymphocytes: Comparing in vivo and in vitro measurements.

Seminars in cell & developmental biology

Avec: Kim S Friedmann , Monika Bozem , Markus Hoth

Loss of Mitochondrial Ca

Circulation

Avec: Edoardo Bertero , Alexander Nickel , Michael Kohlhaas , Mathias Hohl , Vasco Sequeira , Carolin Brune , Julia Schwemmlein , Marco Abeßer , Kai Schuh , Ilona Kutschka , Christopher Carlein , Kai Münker , Sarah Atighetchi , Andreas Müller , Andrey Kazakov , Reinhard Kappl , Karina von der Malsburg , Martin van der Laan , Anna-Florentine Schiuma , Michael Böhm , Ulrich Laufs , Markus Hoth , Peter Rehling , Michaela Kuhn , Jan Dudek , Alexander von der Malsburg , Leticia Prates Roma , Christoph Maack

Optoregulated force application to cellular receptors using molecular motors.

Nature communications

Avec: Yijun Zheng , Mitchell K L Han , Renping Zhao , Johanna Blass , Jingnan Zhang , Dennis W Zhou , Jean-Rémy Colard-Itté , Damien Dattler , Arzu Çolak , Markus Hoth , Andrés J García , Bin Qu , Roland Bennewitz , Nicolas Giuseppone , Aránzazu Del Campo

Light-Sheet Scattering Microscopy to Visualize Long-Term Interactions Between Cells and Extracellular Matrix.

Frontiers in immunology

Avec: Xiangda Zhou , Renping Zhao , Archana K Yanamandra , Markus Hoth , Bin Qu

Cytotoxic Efficiency of Human CD8

Frontiers in immunology

Avec: Arne Knörck , Gertrud Schäfer , Dalia Alansary , Josephine Richter , Lorenz Thurner , Markus Hoth , Eva C Schwarz

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.

Seminars in cell & developmental biology

Avec: Lea Kaschek , Sylvia Zöphel , Arne Knörck , Markus Hoth

Protein Signatures of NK Cell-Mediated Melanoma Killing Predict Response to Immunotherapies.

Cancer research

Avec: Sabrina Cappello , Hsu-Min Sung , Christian Ickes , Christine S Gibhardt , Adina Vultur , Hilal Bhat , Zhongwen Hu , Patricia Brafford , Andreas Denger , Ioana Stejerean-Todoran , Rixa-Mareike Köhn , Verena Lorenz , Nicolas Künzel , Gabriela Salinas , Hedwig Stanisz , Tobias Legler , Peter Rehling , Michael P Schön , Karl S Lang , Volkhard Helms , Meenhard Herlyn , Markus Hoth , Carsten Kummerow , Ivan Bogeski

The B-cell Receptor Autoantigen LRPAP1 Can Replace Variable Antibody Regions to Target Mantle Cell Lymphoma Cells.

HemaSphere

Avec: Moritz Bewarder , Maximilian Kiefer , Helene Will , Kathrin Olesch , Clara Moelle , Stephan Stilgenbauer , Konstantinos Christofyllakis , Dominic Kaddu-Mulindwa , Joerg Thomas Bittenbring , Natalie Fadle , Evi Regitz , Lea Kaschek , Markus Hoth , Frank Neumann , Klaus-Dieter Preuss , Michael Pfreundschuh , Lorenz Thurner

KIR2DS1-HLA-C status as a predictive marker for benefit from rituximab: a post-hoc analysis of the RICOVER-60 and CLL8 trials.

The Lancet. Haematology

Avec: Dominic Kaddu-Mulindwa , Bettina Altmann , Sandra Robrecht , Marita Ziepert , Evi Regitz , Eugen Tausch , Gerhard Held , Viola Poeschel , Vadim Lesan , Joerg Thomas Bittenbring , Lorenz Thurner , Michael Pfreundschuh , Konstantinos Christofyllakis , Lorenz Truemper , Markus Loeffler , Norbert Schmitz , Markus Hoth , Michael Hallek , Kirsten Fischer , Stephan Stilgenbauer , Moritz Bewarder , Torben Millard Rixecker

Interdependence of sequential cytotoxic T lymphocyte and natural killer cell cytotoxicity against melanoma cells.

The Journal of physiology

Avec: Kim S Friedmann , Lea Kaschek , Arne Knörck , Sabrina Cappello , Niklas Lünsmann , Nadja Küchler , Cora Hoxha , Gertrud Schäfer , Sandra Iden , Ivan Bogeski , Carsten Kummerow , Eva C Schwarz , Markus Hoth

B-cell receptor reactivity against

Haematologica

Avec: Lorenz Thurner , Natalie Fadle , Evi Regitz , Sophie Roth , Onur Cetin , Igor Age Kos , Simon Mauro Hess , Julia Bein , Rainer Maria Bohle , Martine Vornanen , Christer Sundström , Laurence De Leval , Enrico Tiacci , Peter Borchmann , Andreas Engert , Viola Poeschel , Gerhard Held , Eva C Schwarz , Frank Neumann , Klaus-Dieter Preuss , Markus Hoth , Ralf Küppers , Karola Lehman , Martin-Leo Hansmann , Sören L Becker , Moritz Bewarder , Sylvia Hartmann

Targeting the Microtubule-Network Rescues CTL Killing Efficiency in Dense 3D Matrices.

Frontiers in immunology

Avec: Renping Zhao , Xiangda Zhou , Essak S Khan , Dalia Alansary , Kim S Friedmann , Wenjuan Yang , Eva C Schwarz , Aránzazu Del Campo , Markus Hoth , Bin Qu

Blockade of PD-1 decreases neutrophilic inflammation and lung damage in experimental COPD.

American journal of physiology. Lung cellular and molecular physiology

Avec: Felix Ritzmann , Kai Borchardt , Giovanna Vella , Praneeth Chitirala , Adrian Angenendt , Christian Herr , Michael D Menger , Markus Hoth , Annette Lis , Rainer M Bohle , Robert Bals , Christoph Beisswenger

Ars2-containing bispecific, Fab- and IgG1-format BAR-bodies to target DLBCL cells.

EJHaem

Avec: Maximilian Kiefer , Lorenz Thurner , Theresa Bock , Onur Cetin , Igor Kos , Vadim Lesan , Dominic Kaddu-Mulindwa , Joerg Thomas Bittenbring , Natalie Fadle , Evi Regitz , Markus Hoth , Frank Neumann , Klaus-Dieter Preuss , Michael Pfreundschuh , Konstantinos Christofyllakis , Moritz Bewarder

CD16+ as predictive marker for early relapse in aggressive B-NHL/DLBCL patients.

Molecular cancer

Avec: Sylvia Zöphel , Nadja Küchler , Johanna Jansky , Cora Hoxha , Gertrud Schäfer , Julius J Weise , Joanne Vialle , Lea Kaschek , Gebhard Stopper , Hermann Eichler , Daniela Yildiz , Alina Moter , Philipp Wendel , Evelyn Ullrich , Claudia Schormann , Torben Rixecker , Onur Cetin , Frank Neumann , Patrick Orth , Moritz Bewarder , Markus Hoth , Lorenz Thurner , Eva C Schwarz

Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry.

Cell reports

Avec: Christine Silvia Gibhardt , Sabrina Cappello , Rajesh Bhardwaj , Romana Schober , Sonja Agnes Kirsch , Zuriñe Bonilla Del Rio , Stefan Gahbauer , Anna Bochicchio , Magdalena Sumanska , Christian Ickes , Ioana Stejerean-Todoran , Miso Mitkovski , Dalia Alansary , Xin Zhang , Aram Revazian , Marc Fahrner , Victoria Lunz , Irene Frischauf , Ting Luo , Daria Ezerina , Joris Messens , Vsevolod Vadimovich Belousov , Markus Hoth , Rainer Arnold Böckmann , Matthias Albrecht Hediger , Rainer Schindl , Ivan Bogeski

Micropatterned soft hydrogels to study the interplay of receptors and forces in T cell activation.

Acta biomaterialia

Avec: Jingnan Zhang , Renping Zhao , Bin Li , Aleeza Farrukh , Markus Hoth , Bin Qu , Aránzazu Del Campo

Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.

Frontiers in oncology

Avec: Lorenz Thurner , Sylvia Hartmann , Frank Neumann , Markus Hoth , Stephan Stilgenbauer , Ralf Küppers , Klaus-Dieter Preuss , Moritz Bewarder

Integration of the B-Cell Receptor Antigen Neurabin-I/SAMD14 Into an Antibody Format as New Therapeutic Approach for the Treatment of Primary CNS Lymphoma.

Frontiers in oncology

Avec: Moritz Bewarder , Maximilian Kiefer , Clara Moelle , Lisa Goerens , Stephan Stilgenbauer , Konstantinos Christofyllakis , Dominic Kaddu-Mulindwa , Natalie Fadle , Evi Regitz , Frank Neumann , Markus Hoth , Klaus-Dieter Preuss , Michael Pfreundschuh , Lorenz Thurner

The calcium channel modulator 2-APB hydrolyzes in physiological buffers and acts as an effective radical scavenger and inhibitor of the NADPH oxidase 2.

Redox biology

Avec: Ewa Jasmin Slowik , Katerina Stankoska , Nhat Nguyen Bui , Bastian Pasieka , David Conrad , Josef Zapp , Markus Hoth , Ivan Bogeski , Reinhard Kappl

Migration of Cytotoxic T Lymphocytes in 3D Collagen Matrices.

Biophysical journal

Avec: Zeinab Sadjadi , Renping Zhao , Markus Hoth , Bin Qu , Heiko Rieger

IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer.

Scientific reports

Avec: Felix Ritzmann , Christopher Jungnickel , Giovanna Vella , Andreas Kamyschnikow , Christian Herr , Dong Li , Michael M Menger , Adrian Angenendt , Markus Hoth , Annette Lis , Robert Bals , C Beisswenger

CaMKII does not control mitochondrial Ca

The Journal of physiology

Avec: Alexander G Nickel , Michael Kohlhaas , Edoardo Bertero , Daniel Wilhelm , Michael Wagner , Vasco Sequeira , Michael M Kreusser , Matthias Dewenter , Reinhard Kappl , Markus Hoth , Jan Dudek , Johannes Backs , Christoph Maack

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling.

Cell death & disease

Avec: Martin Hart , Barbara Walch-Rückheim , Kim S Friedmann , Stefanie Rheinheimer , Tanja Tänzer , Birgit Glombitza , Martina Sester , Hans-Peter Lenhof , Markus Hoth , Eva C Schwarz , Andreas Keller , Eckart Meese

STIM-Orai Channels and Reactive Oxygen Species in the Tumor Microenvironment.

Cancers

Avec: Janina Frisch , Adrian Angenendt , Markus Hoth , Leticia Prates Roma , Annette Lis

Unspecific CTL Killing Is Enhanced by High Glucose

Frontiers in immunology

Avec: Wenjuan Yang , Andreas Denger , Caroline Diener , Frederic Küppers , Leticia Soriano-Baguet , Gertrud Schäfer , Archana K Yanamandra , Renping Zhao , Arne Knörck , Eva C Schwarz , Martin Hart , Frank Lammert , Leticia Prates Roma , Dirk Brenner , Grigorios Christidis , Volkhard Helms , Eckart Meese , Markus Hoth , Bin Qu

B-cell receptors of EBV-negative Burkitt lymphoma bind modified isoforms of autoantigens.

EJHaem

Avec: Theresa Bock , Moritz Bewarder , Onur Cetin , Natalie Fadle , Evi Regitz , Eva C Schwarz , Jana Held , Sophie Roth , Stefan Lohse , Thorsten Pfuhl , Rabea Wagener , Sigrun Smola , Sören L Becker , Rainer Maria Bohle , Lorenz Trümper , Reiner Siebert , Martin-Leo Hansmann , Michael Pfreundschuh , Hans G Drexler , Markus Hoth , Boris Kubuschok , Klaus Roemer , Klaus-Dieter Preuss , Sylvia Hartmann , Lorenz Thurner

Identification of molecular candidates which regulate calcium-dependent CD8

Molecular immunology

Avec: Sylvia Zöphel , Gertrud Schäfer , Maryam Nazarieh , Verena Konetzki , Cora Hoxha , Eckart Meese , Markus Hoth , Volkhard Helms , Mohamed Hamed , Eva C Schwarz

Faster cytotoxicity with age: Increased perforin and granzyme levels in cytotoxic CD8

Aging cell

Avec: Dorina Zöphel , Adrian Angenendt , Lea Kaschek , Keerthana Ravichandran , Chantal Hof , Sandra Janku , Markus Hoth , Annette Lis

Réseau de co-auteurs

Lorenz Thurner 9 collaborations

Eva C Schwarz 9 collaborations

Moritz Bewarder 8 collaborations

Bin Qu 7 collaborations

Renping Zhao 6 collaborations

Evi Regitz 6 collaborations

Frank Neumann 6 collaborations

Klaus-Dieter Preuss 6 collaborations

Gertrud Schäfer 5 collaborations

Lea Kaschek 5 collaborations

Natalie Fadle 5 collaborations

Michael Pfreundschuh 5 collaborations

Kim S Friedmann 4 collaborations

Arne Knörck 4 collaborations

Ivan Bogeski 4 collaborations

Stephan Stilgenbauer 4 collaborations

Konstantinos Christofyllakis 4 collaborations

Dominic Kaddu-Mulindwa 4 collaborations

Onur Cetin 4 collaborations

Adrian Angenendt 4 collaborations

Annette Lis 4 collaborations

Reinhard Kappl 3 collaborations

Leticia Prates Roma 3 collaborations

Aránzazu Del Campo 3 collaborations

Dalia Alansary 3 collaborations

Sylvia Zöphel 3 collaborations

Sabrina Cappello 3 collaborations

Volkhard Helms 3 collaborations

Maximilian Kiefer 3 collaborations

Joerg Thomas Bittenbring 3 collaborations

Cora Hoxha 3 collaborations

Sylvia Hartmann 3 collaborations

Eckart Meese 3 collaborations

Edoardo Bertero 2 collaborations

Michael Kohlhaas 2 collaborations

Vasco Sequeira 2 collaborations

Peter Rehling 2 collaborations

Jan Dudek 2 collaborations

Christoph Maack 2 collaborations

Jingnan Zhang 2 collaborations

Xiangda Zhou 2 collaborations

Archana K Yanamandra 2 collaborations

Christian Ickes 2 collaborations

Andreas Denger 2 collaborations

Ioana Stejerean-Todoran 2 collaborations

Carsten Kummerow 2 collaborations

Clara Moelle 2 collaborations

Gerhard Held 2 collaborations

Viola Poeschel 2 collaborations

Vadim Lesan 2 collaborations

Nadja Küchler 2 collaborations

Sophie Roth 2 collaborations

Rainer Maria Bohle 2 collaborations

Ralf Küppers 2 collaborations

Martin-Leo Hansmann 2 collaborations

Sören L Becker 2 collaborations

Wenjuan Yang 2 collaborations

Felix Ritzmann 2 collaborations

Giovanna Vella 2 collaborations

Christian Herr 2 collaborations

Robert Bals 2 collaborations

Theresa Bock 2 collaborations

Martin Hart 2 collaborations

Luiza Stankevicins 1 collaboration

Nicolas Ecker 1 collaboration

Emmanuel Terriac 1 collaboration

Paolo Maiuri 1 collaboration

Rouven Schoppmeyer 1 collaboration

Pablo Vargas 1 collaboration

Ana-Maria Lennon-Duménil 1 collaboration

Matthieu Piel 1 collaboration

Karsten Kruse 1 collaboration

Franziska Lautenschläger 1 collaboration

Monika Bozem 1 collaboration

Alexander Nickel 1 collaboration

Mathias Hohl 1 collaboration

Carolin Brune 1 collaboration

Julia Schwemmlein 1 collaboration

Marco Abeßer 1 collaboration

Kai Schuh 1 collaboration

Ilona Kutschka 1 collaboration

Christopher Carlein 1 collaboration

Kai Münker 1 collaboration

Sarah Atighetchi 1 collaboration

Andreas Müller 1 collaboration

Andrey Kazakov 1 collaboration

Karina von der Malsburg 1 collaboration

Martin van der Laan 1 collaboration

Anna-Florentine Schiuma 1 collaboration

Michael Böhm 1 collaboration

Ulrich Laufs 1 collaboration

Michaela Kuhn 1 collaboration

Alexander von der Malsburg 1 collaboration

Yijun Zheng 1 collaboration

Mitchell K L Han 1 collaboration

Johanna Blass 1 collaboration

Dennis W Zhou 1 collaboration

Jean-Rémy Colard-Itté 1 collaboration

Damien Dattler 1 collaboration

Arzu Çolak 1 collaboration

Andrés J García 1 collaboration

Roland Bennewitz 1 collaboration

Nicolas Giuseppone 1 collaboration

Josephine Richter 1 collaboration

Hsu-Min Sung 1 collaboration

Christine S Gibhardt 1 collaboration

Adina Vultur 1 collaboration

Hilal Bhat 1 collaboration

Zhongwen Hu 1 collaboration

Patricia Brafford 1 collaboration

Rixa-Mareike Köhn 1 collaboration

Verena Lorenz 1 collaboration

Nicolas Künzel 1 collaboration

Gabriela Salinas 1 collaboration

Hedwig Stanisz 1 collaboration

Tobias Legler 1 collaboration

Michael P Schön 1 collaboration

Karl S Lang 1 collaboration

Meenhard Herlyn 1 collaboration

Helene Will 1 collaboration

Kathrin Olesch 1 collaboration

Bettina Altmann 1 collaboration

Sandra Robrecht 1 collaboration

Marita Ziepert 1 collaboration

Eugen Tausch 1 collaboration

Lorenz Truemper 1 collaboration

Markus Loeffler 1 collaboration

Norbert Schmitz 1 collaboration

Michael Hallek 1 collaboration

Kirsten Fischer 1 collaboration

Torben Millard Rixecker 1 collaboration

Niklas Lünsmann 1 collaboration

Sandra Iden 1 collaboration

Igor Age Kos 1 collaboration

Simon Mauro Hess 1 collaboration

Julia Bein 1 collaboration

Martine Vornanen 1 collaboration

Christer Sundström 1 collaboration

Laurence De Leval 1 collaboration

Enrico Tiacci 1 collaboration

Peter Borchmann 1 collaboration

Andreas Engert 1 collaboration

Karola Lehman 1 collaboration

Essak S Khan 1 collaboration

Kai Borchardt 1 collaboration

Praneeth Chitirala 1 collaboration

Michael D Menger 1 collaboration

Rainer M Bohle 1 collaboration

Christoph Beisswenger 1 collaboration

Igor Kos 1 collaboration

Johanna Jansky 1 collaboration

Julius J Weise 1 collaboration

Joanne Vialle 1 collaboration

Gebhard Stopper 1 collaboration

Hermann Eichler 1 collaboration

Daniela Yildiz 1 collaboration

Alina Moter 1 collaboration

Philipp Wendel 1 collaboration

Evelyn Ullrich 1 collaboration

Claudia Schormann 1 collaboration

Torben Rixecker 1 collaboration

Patrick Orth 1 collaboration

Christine Silvia Gibhardt 1 collaboration

Rajesh Bhardwaj 1 collaboration

Romana Schober 1 collaboration

Sonja Agnes Kirsch 1 collaboration

Zuriñe Bonilla Del Rio 1 collaboration

Stefan Gahbauer 1 collaboration

Anna Bochicchio 1 collaboration

Magdalena Sumanska 1 collaboration

Miso Mitkovski 1 collaboration

Xin Zhang 1 collaboration

Aram Revazian 1 collaboration

Marc Fahrner 1 collaboration

Victoria Lunz 1 collaboration

Irene Frischauf 1 collaboration

Ting Luo 1 collaboration

Daria Ezerina 1 collaboration

Joris Messens 1 collaboration

Vsevolod Vadimovich Belousov 1 collaboration

Rainer Arnold Böckmann 1 collaboration

Matthias Albrecht Hediger 1 collaboration

Rainer Schindl 1 collaboration

Bin Li 1 collaboration

Aleeza Farrukh 1 collaboration

Lisa Goerens 1 collaboration

Ewa Jasmin Slowik 1 collaboration

Katerina Stankoska 1 collaboration

Nhat Nguyen Bui 1 collaboration

Bastian Pasieka 1 collaboration

David Conrad 1 collaboration

Josef Zapp 1 collaboration

Zeinab Sadjadi 1 collaboration

Heiko Rieger 1 collaboration

Christopher Jungnickel 1 collaboration

Andreas Kamyschnikow 1 collaboration

Dong Li 1 collaboration

Michael M Menger 1 collaboration

C Beisswenger 1 collaboration

Alexander G Nickel 1 collaboration

Daniel Wilhelm 1 collaboration

Michael Wagner 1 collaboration

Michael M Kreusser 1 collaboration

Matthias Dewenter 1 collaboration

Johannes Backs 1 collaboration

Barbara Walch-Rückheim 1 collaboration

Stefanie Rheinheimer 1 collaboration

Tanja Tänzer 1 collaboration

Birgit Glombitza 1 collaboration

Martina Sester 1 collaboration

Hans-Peter Lenhof 1 collaboration

Andreas Keller 1 collaboration

Janina Frisch 1 collaboration

Caroline Diener 1 collaboration

Frederic Küppers 1 collaboration

Leticia Soriano-Baguet 1 collaboration

Frank Lammert 1 collaboration

Dirk Brenner 1 collaboration

Grigorios Christidis 1 collaboration

Jana Held 1 collaboration

Stefan Lohse 1 collaboration

Thorsten Pfuhl 1 collaboration

Rabea Wagener 1 collaboration

Sigrun Smola 1 collaboration

Lorenz Trümper 1 collaboration

Reiner Siebert 1 collaboration

Hans G Drexler 1 collaboration

Boris Kubuschok 1 collaboration

Klaus Roemer 1 collaboration

Maryam Nazarieh 1 collaboration

Verena Konetzki 1 collaboration

Mohamed Hamed 1 collaboration

Dorina Zöphel 1 collaboration

Keerthana Ravichandran 1 collaboration

Chantal Hof 1 collaboration

Sandra Janku 1 collaboration