Faster cytotoxicity with age: Increased perforin and granzyme levels in cytotoxic CD8
CD8+ T cells
CTL
aging
cytotoxicity
granzyme
immunosenescence
perforin
tumor immunology
Journal
Aging cell
ISSN: 1474-9726
Titre abrégé: Aging Cell
Pays: England
ID NLM: 101130839
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
revised:
19
05
2022
received:
28
09
2021
accepted:
24
06
2022
pubmed:
13
7
2022
medline:
19
8
2022
entrez:
12
7
2022
Statut:
ppublish
Résumé
A variety of intrinsic and extrinsic factors contribute to the altered efficiency of CTLs in elderly organisms. In particular, the efficacy of antiviral CD8
Identifiants
pubmed: 35818124
doi: 10.1111/acel.13668
pmc: PMC9381916
doi:
Substances chimiques
Membrane Glycoproteins
0
Pore Forming Cytotoxic Proteins
0
Perforin
126465-35-8
Granzymes
EC 3.4.21.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13668Informations de copyright
© 2022 The Authors. Aging Cell published by Anatomical Society and John Wiley & Sons Ltd.
Références
Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9571-6
pubmed: 15980149
Transpl Int. 2009 Nov;22(11):1041-50
pubmed: 19624493
Aging Cell. 2011 Oct;10(5):853-67
pubmed: 21711441
Curr Opin Immunol. 2014 Aug;29:105-11
pubmed: 24934647
Int Immunol. 2020 Apr 12;32(4):223-231
pubmed: 31967307
J Exp Med. 2008 Mar 17;205(3):711-23
pubmed: 18332179
Int J Mol Sci. 2020 Dec 24;22(1):
pubmed: 33374304
Semin Immunol. 2012 Oct;24(5):365-72
pubmed: 22560928
Front Immunol. 2019 Sep 18;10:2206
pubmed: 31620129
J Biol Chem. 2018 Oct 19;293(42):16348-16363
pubmed: 30190323
J Immunol. 1996 May 15;156(10):3621-30
pubmed: 8621895
J Immunol. 2005 Nov 1;175(9):5895-903
pubmed: 16237082
Eur J Immunol. 2014 Jun;44(6):1870-2
pubmed: 24599783
J Immunol. 1998 Feb 15;160(4):1627-37
pubmed: 9469419
Leukemia. 2016 Feb;30(2):492-500
pubmed: 26369987
Nature. 1999 Oct 14;401(6754):708-12
pubmed: 10537110
Immunity. 2017 Mar 21;46(3):364-378
pubmed: 28329703
J Immunol. 2010 May 1;184(9):5151-9
pubmed: 20368274
Aging Cell. 2022 Aug;21(8):e13668
pubmed: 35818124
Aging health. 2011 Oct 1;7(5):707-718
pubmed: 22121388
J Immunother Cancer. 2018 May 29;6(1):41
pubmed: 29843822
Inflamm Res. 2021 Jan;70(1):11-18
pubmed: 33037881
Immunol Rev. 2005 Jun;205:207-19
pubmed: 15882355
Nat Rev Immunol. 2008 Jul;8(7):512-22
pubmed: 18469829
Exp Mol Med. 1999 Sep 30;31(3):137-41
pubmed: 10551262
Semin Immunol. 2012 Oct;24(5):356-64
pubmed: 22554418
J Immunol Methods. 2003 Oct 1;281(1-2):65-78
pubmed: 14580882
J Exp Med. 2001 Dec 17;194(12):1835-46
pubmed: 11748284
PLoS One. 2015 Aug 21;10(8):e0135994
pubmed: 26296096
J Physiol. 2018 Jul;596(14):2681-2698
pubmed: 29368348
Blood. 2000 May 1;95(9):2860-8
pubmed: 10779432
Annu Rev Immunol. 2018 Apr 26;36:411-433
pubmed: 29677473
Front Immunol. 2018 Dec 20;9:2987
pubmed: 30619342
J Immunol. 2012 Feb 15;188(4):1933-41
pubmed: 22246631
Blood. 2004 Apr 15;103(8):3065-72
pubmed: 15070686
J Immunol. 2008 Aug 1;181(3):1835-48
pubmed: 18641321
Nat Immunol. 2018 Jan;19(1):10-19
pubmed: 29242543
Aging (Albany NY). 2020 Feb 12;12(4):3266-3286
pubmed: 32062611
Exp Gerontol. 2013 Jun;48(6):579-86
pubmed: 23473930
Clin Cancer Res. 2011 Jul 1;17(13):4550-7
pubmed: 21498393
Eur J Immunol. 2011 May;41(5):1352-64
pubmed: 21469120
Annu Rev Immunol. 2007;25:171-92
pubmed: 17129182
J Immunol. 1998 Apr 1;160(7):3236-43
pubmed: 9531279
Immunology. 1988 Jul;64(3):457-61
pubmed: 3137156
Eur J Immunol. 2016 Oct;46(10):2286-2301
pubmed: 27595500
Biogerontology. 2017 Aug;18(4):717-721
pubmed: 28220304