Quality of Life Outcomes in Patients With Sinonasal Malignancy After Definitive Treatment.
Aged
Anxiety
/ psychology
Depression
/ psychology
Female
Humans
Male
Middle Aged
Nasal Surgical Procedures
/ psychology
Paranasal Sinus Neoplasms
/ psychology
Postoperative Complications
/ psychology
Quality of Life
/ psychology
Retrospective Studies
Social Support
Surveys and Questionnaires
Treatment Outcome
Quality of life
anxiety
definitive surgery
depression
sinonasal malignancy
Journal
The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
revised:
02
12
2020
received:
21
10
2020
accepted:
09
12
2020
pubmed:
29
12
2020
medline:
29
6
2021
entrez:
28
12
2020
Statut:
ppublish
Résumé
To describe multidimensional quality of life (QOL) outcomes in patients with sinonasal malignancies (SNM). To elucidate factors predicting worse QOL in this population. Retrospective chart review at tertiary institution. A retrospective chart review on patients treated for SNM from 2006 to 2019 at a tertiary medical center was conducted. QOL outcomes were measured using the Hospital Anxiety and Depression Scale (HADS) and the Functional Assessment Cancer Therapy - Nasopharynx (FACT-NP) score. A stepwise multiple linear regression analysis was conducted to assess factors predicting worse QOL. Eighty-one patients met inclusion criteria. Twelve (14.8%) patients had a subscale score >11 for anxiety (HADS-A) or depression (HADS-D) indicating significant anxiety or depression, at a median of 24 (8-68.5) months post treatment. The median FACT-NP total score was 136 (110-152). On multivariable analysis, advanced T classification, single status, and worse social support survey score were significant predictors of worse HADS score. Worse social support survey score was a significant predictor of worse total FACT-NP score. After adjusting for confounders, at a median of 24 months after completion of definitive therapy for SNM, advanced T classification and single relationship status were found to be significant predictors of anxiety and depression (based on HADS). A worse social support survey score was associated with worse anxiety, depression, and QOL (based on HADS and FACT-NP). Identifying these factors early may help to guide treatment and psychiatric referral to at-risk individuals after the treatment of SNM. 3 Laryngoscope, 131:E2212-E2221, 2021.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
E2212-E2221Informations de copyright
© 2020 The American Laryngological, Rhinological and Otological Society, Inc.
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