Imaging spectrum of adverse events of immune checkpoint inhibitors.


Journal

Clinical radiology
ISSN: 1365-229X
Titre abrégé: Clin Radiol
Pays: England
ID NLM: 1306016

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 18 08 2020
accepted: 20 11 2020
pubmed: 31 12 2020
medline: 12 8 2021
entrez: 30 12 2020
Statut: ppublish

Résumé

Immune checkpoint inhibitors (ICIs), a form of immunotherapy, are increasingly used for a variety of malignancies and have been linked to numerous treatment-related side effects known as immune-related adverse events (irAEs). IrAEs can affect multiple organ systems and are important to recognise in order to avoid misinterpretation as progressive tumour and to ensure appropriate management. In this pictorial review, we will briefly discuss radiological response criteria of immunotherapy and describe the imaging appearances of the wide spectrum of these ICI-associated toxicities.

Identifiants

pubmed: 33375984
pii: S0009-9260(20)30625-5
doi: 10.1016/j.crad.2020.11.117
pii:
doi:

Substances chimiques

Immune Checkpoint Inhibitors 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

262-272

Informations de copyright

Copyright © 2020 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Auteurs

G S Shroff (GS)

MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 1478, Houston, TX, 77030, USA. Electronic address: gshroff@mdanderson.org.

S Shroff (S)

Houston Methodist, 6560 Fannin St. Ste 802, Houston, TX, 77030, USA.

J Ahuja (J)

MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 1478, Houston, TX, 77030, USA.

M T Truong (MT)

MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 1478, Houston, TX, 77030, USA.

I Vlahos (I)

MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 1478, Houston, TX, 77030, USA.

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Classifications MeSH