[Research progress on the biomimetic remineralization of hard tooth tissues based on polyamide-amine dendrimer].
biomimetic mineralization
hard tooth tissue
polyamide-amine dendrimer
Journal
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
ISSN: 2618-0456
Titre abrégé: Hua Xi Kou Qiang Yi Xue Za Zhi
Pays: China
ID NLM: 9422648
Informations de publication
Date de publication:
01 Dec 2020
01 Dec 2020
Historique:
entrez:
30
12
2020
pubmed:
31
12
2020
medline:
1
1
2021
Statut:
ppublish
Résumé
Polyamide-amine (PAMAM) dendrimer, a new hyperbranched macromolecular polymer, is considered an "artificial protein" by many scholars on account of its excellent chemical and biological characteristics. PAMAM has internal cavities and a large number of reactive terminal groups. These structures allow the polymer to be used as a bionic macromoleculethat could simulate the biomimetic mineralization of the natural organic matrix on the surface of tooth tissue. Specifically, PAMAM can beused as an organic template to regulate mineral nucleation and crystal growth; thus, the polymerisa more ideal dental restoration material than traditional allogenic materials. This article reviews research progress on thePAMAM-induced biomimetic mineralization of hard tooth tissues. 聚酰胺—胺树枝状聚合物（PAMAM）作为一种新型超支化大分子聚合物，因其出色的化学和生物学特性，一直被众学者称之为“人工蛋白”。 PAMAM的特点是存在内部空腔，并含有大量的反应性末端基团，这些结构使得PAMAM可以被用作仿生大分子，模拟天然有机基质在牙体组织表面进行仿生矿化，即PAMAM作为有机模板调控矿物质成核以及晶体的生长，以此来建造比传统的异体材料更加理想的牙体修复材料。本文就 PAMAM 诱导牙体硬组织仿生矿化的研究进展作一综述。.
Autres résumés
Type: Publisher
(chi)
聚酰胺—胺树枝状聚合物（PAMAM）作为一种新型超支化大分子聚合物，因其出色的化学和生物学特性，一直被众学者称之为“人工蛋白”。 PAMAM的特点是存在内部空腔，并含有大量的反应性末端基团，这些结构使得PAMAM可以被用作仿生大分子，模拟天然有机基质在牙体组织表面进行仿生矿化，即PAMAM作为有机模板调控矿物质成核以及晶体的生长，以此来建造比传统的异体材料更加理想的牙体修复材料。本文就 PAMAM 诱导牙体硬组织仿生矿化的研究进展作一综述。.
Identifiants
pubmed: 33377349
doi: 10.7518/hxkq.2020.06.015
pmc: PMC7738911
doi:
Substances chimiques
Amines
0
Dendrimers
0
Nylons
0
Types de publication
Journal Article
Review
Langues
chi
Sous-ensembles de citation
IM
Pagination
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