Determination of amino acids by capillary and microchip electrophoresis with contactless conductivity detection - Theory, instrumentation and applications.
Amino acid
Capillary electrophoresis
Clinical analysis
Contactless conductivity detection
Food analysis
Microchip electrophoresis
Microdialysis
Sample treatment
Stacking
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
01 Mar 2021
01 Mar 2021
Historique:
received:
27
10
2020
revised:
22
11
2020
accepted:
23
11
2020
entrez:
31
12
2020
pubmed:
1
1
2021
medline:
15
5
2021
Statut:
ppublish
Résumé
This review article summarises aspects of the determination of amino acids using capillary and chip electrophoresis in combination with contactless conductivity detection from their historical beginnings to the present time. Discussion is included of the theory of conductivity detection in electromigration techniques, the design of contactless conductivity cells for detection in capillaries and on microchips, including the use of computer programs for simulation of the conductivity response and the process of the electrophoretic separation of amino acids. Emphasis is placed on optimisation of the background electrolyte composition, chiral separation, multidimensional separation, stacking techniques and the use of multidetection systems. There is also a description of clinical applications, the determination of amino acids in foodstuffs, waters, soils and composts with emphasis on modern techniques of sample treatment, such as microdialysis, liquid membrane extraction and many other techniques.
Identifiants
pubmed: 33379123
pii: S0039-9140(20)31213-3
doi: 10.1016/j.talanta.2020.121922
pii:
doi:
Substances chimiques
Amino Acids
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
121922Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.