Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.
Adolescent
Adult
Aged
Aged, 80 and over
Antibodies, Viral
/ blood
Antigens, CD19
/ metabolism
Antigens, CD20
/ metabolism
B-Lymphocytes
/ immunology
Case-Control Studies
Cell Proliferation
Communicable Diseases
/ blood
Encephalitis Viruses, Tick-Borne
/ immunology
Female
Humans
Immunity, Humoral
Immunogenicity, Vaccine
Inflammation
/ blood
Influenza Vaccines
/ administration & dosage
Lymphocyte Activation
Male
Middle Aged
Phenotype
Transcriptome
Tumor Necrosis Factor Receptor Superfamily, Member 7
/ metabolism
Vaccination
Viral Vaccines
/ administration & dosage
Young Adult
B cells
TBE vaccination
autoimmune disorders
double negative B cells
influenza vaccination
neuromyelitis optica spectrum disorder
vaccination
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2020
2020
Historique:
received:
14
09
2020
accepted:
17
11
2020
entrez:
4
1
2021
pubmed:
5
1
2021
medline:
22
6
2021
Statut:
epublish
Résumé
Double negative (DN) (CD19
Identifiants
pubmed: 33391273
doi: 10.3389/fimmu.2020.606338
pmc: PMC7775384
doi:
Substances chimiques
Antibodies, Viral
0
Antigens, CD19
0
Antigens, CD20
0
CD19 molecule, human
0
Influenza Vaccines
0
Tumor Necrosis Factor Receptor Superfamily, Member 7
0
Viral Vaccines
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
606338Subventions
Organisme : NEI NIH HHS
ID : R01 EY022936
Pays : United States
Informations de copyright
Copyright © 2020 Ruschil, Gabernet, Lepennetier, Heumos, Kaminski, Hracsko, Irmler, Beckers, Ziemann, Nahnsen, Owens, Bennett, Hemmer and Kowarik.
Déclaration de conflit d'intérêts
UZ Has received grants from European Research Council (ERC), German Research Foundation (DFG), German Federal Ministry of Education and Research (BMBF), Bristol Myers Squibb, Janssen Pharmaceutica NV, Servier, Biogen Idec GmbH, and personal fees from Bayer Vital GmbH, Pfizer GmbH, CorTec GmbH, all not related to this work. JLB serves as a consultant for Clene Nanomedicine, Viela Bio, Chugai Pharmaceutical, EMD Serono, Equillium, Alexion, Roche, Genentech, and Novartis; and receives research support from Mallinckrodt. BH has served on scientific advisory boards for Novartis; he has served as DMSC member for AllergyCare and TG therapeutics; he or his institution has received speaker honoraria from Desitin; holds part of two patents; one for the detection of antibodies against KIR4.1 in a subpopulation of MS patients and one for genetic determinants of neutralizing antibodies to interferon. All conflicts are not relevant to the topic of the study. MK receives financial support from Merck, Sanofi-Genzyme, Novartis, Biogen, Celgene, and Roche, all not related to this study. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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