Assessment of salt intake to consider salt as a fortification vehicle for thiamine in Cambodia.
Adult
Cambodia
/ epidemiology
Dietary Supplements
Disease Management
Disease Susceptibility
Family Characteristics
Female
Food, Fortified
Humans
Male
Pregnancy
Public Health Surveillance
Sociodemographic Factors
Sodium Chloride, Dietary
/ administration & dosage
Thiamine
/ administration & dosage
Thiamine Deficiency
/ epidemiology
beriberi
fortification
human milk
salt
thiamine
urinary sodium
Journal
Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
revised:
08
12
2020
received:
05
10
2020
accepted:
17
12
2020
pubmed:
9
1
2021
medline:
15
12
2021
entrez:
8
1
2021
Statut:
ppublish
Résumé
Thiamine deficiency is a public health issue in Cambodia. Thiamine fortification of salt has been proposed; however, the salt intake of lactating women, the target population, is currently unknown. We estimated salt intakes among lactating women (<6 months postpartum) using three methods: repeat observed-weighed intake records and 24-h urinary sodium excretions (n = 104), and household salt disappearance (n = 331). Usual salt intake was estimated by adjusting for intraindividual intakes using the National Cancer Institute method, and a thiamine salt fortification scenario was modeled using a modified estimated average requirement (EAR) cut-point method. Unadjusted salt intake from observed intakes was 9.3 (8.3-10.3) g/day, which was not different from estimated salt intake from urinary sodium excretions, 9.0 (8.4-9.7) g/day (P = 0.3). Estimated salt use from household salt disappearance was 11.3 (10.7-11.9) g/person/day. Usual (adjusted) salt intake from all sources was 7.7 (7.4-8.0) g/day. Assuming no stability losses, a modeled fortification dose of 275 mg thiamine/kg salt could increase thiamine intakes from fortified salt to 2.1 (2.0-2.2) mg/day, with even low salt consumers reaching the EAR of 1.2 mg/day from fortified salt alone. These findings, in conjunction with future sensory and stability research, can inform a potential salt fortification program in Cambodia.
Identifiants
pubmed: 33415757
doi: 10.1111/nyas.14562
pmc: PMC8451827
doi:
Substances chimiques
Sodium Chloride, Dietary
0
Thiamine
X66NSO3N35
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
85-95Informations de copyright
© 2021 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals LLC on behalf of New York Academy of Sciences.
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