Impaired DNA repair in mouse monocytes compared to macrophages and precursors.
Animals
Apoptosis
DNA
/ drug effects
DNA Breaks, Double-Stranded
DNA Damage
DNA Ligase ATP
/ genetics
DNA Repair
DNA-Activated Protein Kinase
/ genetics
DNA-Binding Proteins
/ genetics
Female
Gamma Rays
Gene Expression Regulation
Histones
/ analysis
Macrophages
/ drug effects
Mice
Mice, Inbred C57BL
Monocytes
/ drug effects
Poly (ADP-Ribose) Polymerase-1
/ genetics
Poly-ADP-Ribose Binding Proteins
/ genetics
Stem Cells
/ drug effects
Temozolomide
/ pharmacology
X-ray Repair Cross Complementing Protein 1
/ genetics
Genotoxicants
Macrophages
Monocyte maturation
Monocytes
Stem cells
Journal
DNA repair
ISSN: 1568-7856
Titre abrégé: DNA Repair (Amst)
Pays: Netherlands
ID NLM: 101139138
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
14
10
2020
revised:
20
11
2020
accepted:
21
12
2020
pubmed:
9
1
2021
medline:
5
8
2021
entrez:
8
1
2021
Statut:
ppublish
Résumé
Previously we showed that human monocytes isolated from peripheral blood display downregulation of several DNA repair proteins, including XRCC1, ligase III, PARP-1 and DNA-PK
Identifiants
pubmed: 33418482
pii: S1568-7864(20)30297-4
doi: 10.1016/j.dnarep.2020.103037
pii:
doi:
Substances chimiques
DNA-Binding Proteins
0
Histones
0
Poly-ADP-Ribose Binding Proteins
0
X-ray Repair Cross Complementing Protein 1
0
Xrcc1 protein, mouse
0
gamma-H2AX protein, mouse
0
DNA
9007-49-2
Parp1 protein, mouse
EC 2.4.2.30
Poly (ADP-Ribose) Polymerase-1
EC 2.4.2.30
DNA-Activated Protein Kinase
EC 2.7.11.1
Prkdc protein, mouse
EC 2.7.11.1
DNA Ligase ATP
EC 6.5.1.1
Lig3 protein, mouse
EC 6.5.1.1
Temozolomide
YF1K15M17Y
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
103037Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.