Conditioned Medium from Human Amnion-Derived Mesenchymal Stromal/Stem Cells Attenuating the Effects of Cold Ischemia-Reperfusion Injury in an In Vitro Model Using Human Alveolar Epithelial Cells.
A549 Cells
Alveolar Epithelial Cells
/ drug effects
Amnion
/ cytology
Apoptosis
/ drug effects
Cell Cycle
/ drug effects
Cell Differentiation
/ drug effects
Cell Survival
/ drug effects
Cells, Cultured
Cold Ischemia
/ methods
Culture Media, Conditioned
/ pharmacology
Cytokines
/ genetics
Gene Expression Regulation
/ drug effects
Humans
Mesenchymal Stem Cells
/ cytology
NF-kappa B
/ genetics
Reperfusion Injury
/ drug therapy
amnion-derived mesenchymal stem cells
conditioned medium
ex vivo lung perfusion
lung ischemia-reperfusion injury
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
06 Jan 2021
06 Jan 2021
Historique:
received:
16
11
2020
revised:
30
12
2020
accepted:
03
01
2021
entrez:
9
1
2021
pubmed:
10
1
2021
medline:
14
9
2021
Statut:
epublish
Résumé
The clinical results of lung transplantation (LTx) are still less favorable than other solid organ transplants in both the early and long term. The fragility of the lungs limits the procurement rate and can favor the occurrence of ischemia-reperfusion injury (IRI). Ex vivo lung perfusion (EVLP) with Steen Solution
Identifiants
pubmed: 33419219
pii: ijms22020510
doi: 10.3390/ijms22020510
pmc: PMC7825633
pii:
doi:
Substances chimiques
Culture Media, Conditioned
0
Cytokines
0
NF-kappa B
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Medical Center, University of Pittsburgh
ID : I00000171
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : CTN01_00177_888744
Références
N Engl J Med. 2011 Apr 14;364(15):1431-40
pubmed: 21488765
Int J Mol Sci. 2019 Nov 05;20(21):
pubmed: 31694240
Can Respir J. 2015 Jan-Feb;22(1):47-51
pubmed: 25379654
Stem Cell Res Ther. 2017 Jul 5;8(1):159
pubmed: 28676074
Stem Cells Transl Med. 2015 May;4(5):448-58
pubmed: 25824141
J Neurosci Res. 2015 Jun;93(6):973-83
pubmed: 25663284
Curr Opin Organ Transplant. 2016 Jun;21(3):246-52
pubmed: 26945320
Stem Cells Int. 2019 Feb 18;2019:7486279
pubmed: 30911299
J Heart Lung Transplant. 2014 Oct;33(10):1093-9
pubmed: 25043623
J Mol Med (Berl). 2019 Apr;97(4):437-450
pubmed: 30729280
Int J Clin Exp Pathol. 2013 Apr 15;6(5):831-40
pubmed: 23638214
Chest Surg Clin N Am. 2003 Aug;13(3):443-62
pubmed: 13678307
Protein Cell. 2020 Oct;11(10):707-722
pubmed: 32519302
Transpl Int. 2015 Jan;28(1):1-9
pubmed: 25082213
J Thorac Dis. 2017 Aug;9(8):2684-2691
pubmed: 28932576
Surg Today. 2017 Apr;47(4):425-431
pubmed: 27484066
Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13724-9
pubmed: 20643923
Int J Cardiol. 2016 Aug 1;216:173-85
pubmed: 27156061
J Thorac Dis. 2016 Jun;8(6):1234-44
pubmed: 27293842
J Pathol. 2000 Feb;190(3):255-66
pubmed: 10685060
Cell Biosci. 2015 Aug 20;5:45
pubmed: 26294957
Biomed J. 2019 Feb;42(1):36-45
pubmed: 30987703
Stem Cell Rev Rep. 2015 Feb;11(1):150-60
pubmed: 25091427
J Thorac Cardiovasc Surg. 2016 Mar;151(3):841-849
pubmed: 26896360
Transplant Res. 2014 Nov 01;3(1):19
pubmed: 25671090
Eur Cytokine Netw. 2013 Mar;24(1):11-9
pubmed: 23661360
Cells. 2020 May 28;9(6):
pubmed: 32481562
J Immunol Res. 2018 Jun 24;2018:5083797
pubmed: 30035132
Lung. 2015 Feb;193(1):85-95
pubmed: 25344633
J Int Med Res. 2004 Mar-Apr;32(2):124-31
pubmed: 15080015
PLoS One. 2012;7(10):e46956
pubmed: 23071674
J Thorac Cardiovasc Surg. 2019 Sep 9;:
pubmed: 31606173
Biomed Res Int. 2019 Mar 3;2019:6376271
pubmed: 30941369
PLoS One. 2018 Sep 13;13(9):e0202772
pubmed: 30212490
PLoS One. 2009 Aug 06;4(8):e6537
pubmed: 19657392
Front Immunol. 2020 Feb 12;11:54
pubmed: 32117234
Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16357-62
pubmed: 19721001
PLoS One. 2013;8(1):e52419
pubmed: 23349686
J Clin Med. 2020 Mar 03;9(3):
pubmed: 32138309
J Cardiothorac Surg. 2014 Sep 02;9:151
pubmed: 25179441
Ann Thorac Surg. 2016 Aug;102(2):385-393
pubmed: 27109193
Transpl Int. 2016 Nov;29(11):1237-1246
pubmed: 27514498
Mol Med Rep. 2016 Feb;13(2):1517-24
pubmed: 26718099
Stem Cells. 2008 Feb;26(2):300-11
pubmed: 17975221
Int J Mol Sci. 2020 Jun 19;21(12):
pubmed: 32575596
Cell Mol Life Sci. 2020 Jul;77(14):2771-2794
pubmed: 31965214
Mol Ther. 2012 Jul;20(7):1424-33
pubmed: 22453767
J Cell Mol Med. 2017 Jun;21(6):1139-1149
pubmed: 27957793
Am J Respir Crit Care Med. 2003 Feb 15;167(4):490-511
pubmed: 12588712
J Heart Lung Transplant. 2016 Oct;35(10):1245-1254
pubmed: 27444694
Placenta. 2016 Dec;48:99-103
pubmed: 27871479
Curr Opin Organ Transplant. 2015 Oct;20(5):515-20
pubmed: 26348570
Stem Cells Transl Med. 2015 Sep;4(9):980-92
pubmed: 26198166
Biochem Biophys Res Commun. 2020 Jan 29;522(1):171-176
pubmed: 31757423
Acta Pharm Sin B. 2020 Sep;10(9):1634-1645
pubmed: 33088684
J Clin Invest. 2008 Mar;118(3):913-23
pubmed: 18259607
Cytotherapy. 2012 Feb;14(2):153-61
pubmed: 21954836
Ann Transl Med. 2020 Mar;8(6):412
pubmed: 32355856
Curr Res Transl Med. 2020 Nov;68(4):217-224
pubmed: 32843323
Int J Mol Sci. 2020 Jul 28;21(15):
pubmed: 32731615
J Transl Med. 2011 Jul 22;9:118
pubmed: 21781312
Ann Thorac Surg. 2016 Dec;102(6):1845-1853
pubmed: 27614736
Iran J Basic Med Sci. 2019 Nov;22(11):1253-1258
pubmed: 32128088
Stem Cells Transl Med. 2020 Sep;9(9):985-1006
pubmed: 32497410
Stem Cells. 2012 Oct;30(10):2283-96
pubmed: 22865689
FASEB J. 2006 Dec;20(14):2624-6
pubmed: 17142801
Compr Physiol. 2016 Dec 6;7(1):113-170
pubmed: 28135002
Curr Stem Cell Res Ther. 2013 Jan;8(1):6-14
pubmed: 23270631
Kidney Int. 2002 Oct;62(4):1160-70
pubmed: 12234286
PLoS One. 2012;7(10):e47559
pubmed: 23133515
Biomed Res Int. 2020 Mar 27;2020:9847579
pubmed: 32309444
Am J Respir Crit Care Med. 2017 Nov 15;196(10):1275-1286
pubmed: 28598224
Stem Cells Transl Med. 2017 Jun;6(6):1557-1567
pubmed: 28425576
J Heart Lung Transplant. 2005 Oct;24(10):1454-9
pubmed: 16210116
Placenta. 2018 May;65:37-46
pubmed: 29908640
J Neuroinflammation. 2018 Jun 22;15(1):189
pubmed: 29933760