Unilateral lower limb atrophy associated with glomus tumors: a case report.


Journal

Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382

Informations de publication

Date de publication:
13 Jan 2021
Historique:
received: 15 10 2020
accepted: 02 12 2020
entrez: 13 1 2021
pubmed: 14 1 2021
medline: 15 5 2021
Statut: epublish

Résumé

Glomus tumors are soft tissue neoplasms comprised of glomus cells, vasculature, and smooth muscle cells, which occur commonly in a single subungual area of the digits, and their main clinical features include severe paroxysmal pain, localized tenderness, and cold hypersensitivity. A 47-year-old Japanese man had suffered from chronic progressive paroxysmal shooting pain in his right leg since childhood. He avoided putting weight on his right foot whenever he walked. The frequency of paroxysmal pain and the number of tender points both gradually increased with age, and his right leg gradually atrophied. Magnetic resonance imaging of the lower extremity demonstrated multiple gadolinium-enhanced nodules that corresponded with his tender points. Excisional biopsy relieved his pain and provided a histopathological diagnosis of glomus tumors. This case suggests that small glomus tumors located in deep tissue may cause disuse atrophy because of their long delay before diagnosis. Clinicians should consider the potential for glomus tumors when patients exhibit unilateral lower limb muscular atrophy with pain.

Sections du résumé

BACKGROUND BACKGROUND
Glomus tumors are soft tissue neoplasms comprised of glomus cells, vasculature, and smooth muscle cells, which occur commonly in a single subungual area of the digits, and their main clinical features include severe paroxysmal pain, localized tenderness, and cold hypersensitivity.
CASE PRESENTATION METHODS
A 47-year-old Japanese man had suffered from chronic progressive paroxysmal shooting pain in his right leg since childhood. He avoided putting weight on his right foot whenever he walked. The frequency of paroxysmal pain and the number of tender points both gradually increased with age, and his right leg gradually atrophied. Magnetic resonance imaging of the lower extremity demonstrated multiple gadolinium-enhanced nodules that corresponded with his tender points. Excisional biopsy relieved his pain and provided a histopathological diagnosis of glomus tumors.
CONCLUSION CONCLUSIONS
This case suggests that small glomus tumors located in deep tissue may cause disuse atrophy because of their long delay before diagnosis. Clinicians should consider the potential for glomus tumors when patients exhibit unilateral lower limb muscular atrophy with pain.

Identifiants

pubmed: 33436045
doi: 10.1186/s13256-020-02616-1
pii: 10.1186/s13256-020-02616-1
pmc: PMC7805226
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8

Références

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J Bone Joint Surg Br. 1992 Sep;74(5):779-80
pubmed: 1326563
J Orthop Case Rep. 2018 Sep-Oct;8(5):22-24
pubmed: 30740368
Pain Med. 2010 Aug;11(8):1267-73
pubmed: 20704675

Auteurs

Yuji Akechi (Y)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

Shiroh Miura (S)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. shiroh46@m.ehime-u.ac.jp.

Masayuki Ochi (M)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

Moe Enoki (M)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

Takuya Matsuda (T)

Department of Radiology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

Riko Kitazawa (R)

Department of Molecular Pathology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

Taketsugu Fujibuchi (T)

Department of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

Hirofumi Ochi (H)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

Michiya Igase (M)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

Yasumasa Ohyagi (Y)

Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

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